SCHEMBL10064656

SCHEMBL10064656

NC(Cc1cc(O)cc(F)c1)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.56
USP2 O75604 4/20 0.51
HSD17B10 Q99714 4/20 0.51
ALOX15 P16050 3/20 0.51
ADORA3 P0DMS8 3/20 0.51
KDM4E B2RXH2 2/20 0.51
PTGS1 P23219 2/20 0.51
RECQL P46063 2/20 0.51
HIF1A Q16665 2/20 0.51
TDP1 Q9NUW8 2/20 0.51
PTGS2 P35354 2/20 0.51
EGFR P00533 1/20 0.51
LCK P06239 1/20 0.51
FYN P06241 1/20 0.51
HTR2A P28223 1/20 0.51
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
LMNA P02545 3/20 0.50
THRB P10828 3/20 0.50
PKM P14618 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31524255 1.00 SLC7A5 (0.56) SLC7A5USP2HSD17B10ALOX15ADORA3
SCHEMBL12803446 1.00 SLC7A5 (0.56) SLC7A5USP2HSD17B10ALOX15ADORA3
SCHEMBL188320 0.89 SLC7A5 (0.57) SLC7A5USP2HSD17B10ALOX15ADORA3
SCHEMBL2129884 0.89 SLC7A5 (0.57) SLC7A5USP2HSD17B10ALOX15ADORA3
SCHEMBL188321 0.89 SLC7A5 (0.57) SLC7A5USP2HSD17B10ALOX15ADORA3
SCHEMBL1483094 0.87 SLC7A5 (0.66) SLC7A5USP2HSD17B10ALOX15ADORA3
SCHEMBL1483095 0.87 SLC7A5 (0.66) SLC7A5USP2HSD17B10ALOX15ADORA3
SCHEMBL5560750 0.83 SLC7A5 (0.56) SLC7A5USP2HSD17B10ALOX15ADORA3
Glycine SCHEMBL28732579 0.83 SLC7A5 (0.50) SLC7A5USP2HSD17B10ALOX15ADORA3
SCHEMBL845967 0.81 SLC7A5 (0.49) SLC7A5USP2HSD17B10ALOX15ADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4568976-A1 SMALL MOLECULES FOR BORON NEUTRON CAPTURE THERAPY Aviko Radiopharmaceuticals, LLC (US) 2025-06-18 EP disclosed
US-20240067665-A1 SMALL MOLECULES FOR BORON NEUTRON CAPTURE THERAPY AVIKO RADIOPHARMACEUTICALS LLC (US) 2024-02-29 US disclosed
US-20240067665-A1 SMALL MOLECULES FOR BORON NEUTRON CAPTURE THERAPY AVIKO RADIOPHARMACEUTICALS LLC (US) 2024-02-29 US disclosed
US-20240067665-A1 SMALL MOLECULES FOR BORON NEUTRON CAPTURE THERAPY AVIKO RADIOPHARMACEUTICALS LLC (US) 2024-02-29 US disclosed
WO-2024035871-A1 SMALL MOLECULES FOR BORON NEUTRON CAPTURE THERAPY AVIKO RADIOPHARMACEUTICALS, LLC (US) 2024-02-15 WO disclosed
EP-3427737-A1 SANGLIFEHRIN DERIVATIVES AND METHODS FOR THEIR PRODUCTION NeuroVive Pharmaceutical AB (SE) 2019-01-16 EP disclosed
EP-2770977-B1 NOVEL DOSAGE FORM NEUROVIVE PHARMACEUTICAL AB (SE) 2017-07-12 EP disclosed
EP-2770977-B1 NOVEL DOSAGE FORM NEUROVIVE PHARMACEUTICAL AB (SE) 2017-07-12 EP disclosed
US-9504728-B2 Dosage form NEUROVIVE PHARMACEUTICAL AB (SE) 2016-11-29 US disclosed
US-9504728-B2 Dosage form NEUROVIVE PHARMACEUTICAL AB (SE) 2016-11-29 US disclosed
US-20140038885-A1 Macrocyclic Compounds and Methods for Their Production NEUROVIVE PHARMACEUTICAL AB (SE) 2014-02-06 US disclosed
US-20140038885-A1 Macrocyclic Compounds and Methods for Their Production NEUROVIVE PHARMACEUTICAL AB (SE) 2014-02-06 US disclosed
US-20140038885-A1 Macrocyclic Compounds and Methods for Their Production NEUROVIVE PHARMACEUTICAL AB (SE) 2014-02-06 US disclosed
WO-2013061052-A1 NOVEL DOSAGE FORM BIOTICA TECHNOLOGY LIMITED (GB) 2013-05-02 WO disclosed
US-20120251581-A1 Novel Compound and Methods for its Production Abliva Ab (SE) 2012-10-04 US disclosed
US-20120251581-A1 Novel Compound and Methods for its Production Abliva Ab (SE) 2012-10-04 US disclosed
US-20120251581-A1 Novel Compound and Methods for its Production Abliva Ab (SE) 2012-10-04 US disclosed
WO-2012131371-A1 MACROCYCLIC COMPOUND AND METHODS FOR ITS PRODUCTION BIOTICA TECHNOLOGY LIMITED (GB) 2012-10-04 WO disclosed
WO-2012131377-A1 MACROCYCLIC COMPOUNDS AND METHODS FOR THEIR PRODUCTION BIOTICA TECHNOLOGY LIMITED (GB) 2012-10-04 WO disclosed
WO-2012085553-A1 SANGLIFEHRIN DERIVATIVES AND METHODS FOR THEIR PRODUCTION BIOTICA TECHNOLOGY LIMITED (GB) 2012-06-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240067665-A1 SMALL MOLECULES FOR BORON NEUTRON CAPTURE THERAPY NME2, BTD, BLVRB SLC7A5 56/4885USP2 2664/4885HSD17B10 3071/4885
US-20140038885-A1 Macrocyclic Compounds and Methods for Their Production HAVCR2, RPL35, CD4 SLC7A5 1425/4885USP2 4542/4885HSD17B10 1042/4885
US-20120251581-A1 Novel Compound and Methods for its Production EIF2AK2, HAVCR2, CYP51A1 SLC7A5 2824/4885USP2 3987/4885HSD17B10 642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.