Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3148481 | 0.85 | GRM2 (0.41) | LTA4HMEN1KMT2ARAB9AACHE | |
| SCHEMBL3149566 | 0.84 | MAP4K4 (0.41) | MEN1KMT2ARAB9AACHEMAPT | |
| SCHEMBL17083311 | 0.83 | PYCR1 (0.50) | LTA4HMEN1KMT2ARAB9AMAPT | |
| SCHEMBL8425241 | 0.82 | MAPT (0.48) | MAPTHIF1AKDM4ETDP1 | |
| SCHEMBL304452 | 0.82 | RAB9A (0.55) | LTA4HMEN1KMT2ARAB9AACHE | |
| SCHEMBL16590371 | 0.81 | KMT2A (0.57) | LTA4HMEN1KMT2AMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL5760483 | 0.81 | RAB9A (0.53) | LTA4HMEN1KMT2ARAB9AACHE | |
| Potassium SCHEMBL6997235 | 0.81 | RAB9A (0.53) | LTA4HMEN1KMT2ARAB9AACHE | |
| SCHEMBL5205870 | 0.81 | ALDH1A1 (0.41) | MEN1KMT2ARAB9AACHEBCHE | |
| SCHEMBL3153531 | 0.81 | MEN1 (0.45) | MEN1KMT2ARAB9AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2760838-A1 | DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2014-08-06 | — | — | EP | disclosed |
| WO-2013045280-A1 | DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2013-04-04 | — | — | WO | disclosed |