Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 6/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21414009 | 0.85 | MAPT (0.36) | NPC1MAPTALDH1A1HSD17B10GFER | |
| SCHEMBL8510186 | 0.78 | ALDH1A1 (0.41) | NPC1MAPTALDH1A1HSD17B10GFER | |
| SCHEMBL13616793 | 0.76 | ALDH1A1 (0.48) | NPC1MAPTALDH1A1HSD17B10GFER | |
| SCHEMBL19718293 | 0.76 | NPC1 (0.40) | NPC1MAPTALDH1A1HSD17B10GFER | |
| SCHEMBL14096214 | 0.74 | ALDH1A1 (0.39) | NPC1MAPTALDH1A1HSD17B10GFER | |
| SCHEMBL16616805 | 0.73 | NPC1 (0.37) | NPC1MAPTALDH1A1HSD17B10GFER | |
| SCHEMBL14096211 | 0.73 | NPC1 (0.41) | NPC1MAPTALDH1A1HSD17B10GFER | |
| SCHEMBL14832769 | 0.73 | DPP4 (0.47) | NPC1MAPTALDH1A1HSD17B10RXFP1 | |
| SCHEMBL770898 | 0.72 | POLB (0.44) | NPC1MAPTRXFP1RAB9APOLB | |
| SCHEMBL14838320 | 0.72 | SNCA (0.37) | NPC1MAPTALDH1A1HSD17B10GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108690045-B | Diarylethene compounds and uses thereof | 首诺加拿大公司 | 2022-08-30 | — | — | CN | disclosed |
| US-11124524-B2 | Diarylethene compounds and uses thereof | SOLUTIA CANADA INC. (US) | 2021-09-21 | — | — | US | disclosed |
| US-10556912-B2 | Diarylethene compounds and uses thereof | SWITCH MATERIALS, INC. (CA) | 2020-02-11 | — | — | US | disclosed |
| US-20190256526-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | SWITCH MATERIALS, INC. (CA) | 2019-08-22 | — | — | US | disclosed |
| US-20180339995-A1 | PHOTOCHROMIC AND ELECTROCHROMIC DIARYLCYCLOPENTENE DERIVATIVES AS OPTICAL FILTERS | SWITCH MATERIALS, INC. (CA) | 2018-11-29 | — | — | US | disclosed |
| EP-3385354-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | Switch Materials, Inc. (CA) | 2018-10-10 | — | — | EP | disclosed |
| US-10072023-B2 | Diarylethene compounds and uses thereof | SWITCH MATERIALS, INC. (CA) | 2018-09-11 | — | — | US | disclosed |
| EP-2760969-B1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | SWITCH MAT INC (CA) | 2018-05-16 | — | — | EP | disclosed |
| EP-2760969-B1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | SWITCH MAT INC (CA) | 2018-05-16 | — | — | EP | disclosed |
| US-20160083398-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | SWITCH MATERIALS, INC. (CA) | 2016-03-24 | — | — | US | disclosed |
| US-20160083398-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | SWITCH MATERIALS, INC. (CA) | 2016-03-24 | — | — | US | disclosed |
| US-9227986-B2 | Diarylethene compounds and uses thereof | SWITCH MATERIALS, INC. (CA) | 2016-01-05 | — | — | US | disclosed |
| US-9227986-B2 | Diarylethene compounds and uses thereof | SWITCH MATERIALS, INC. (CA) | 2016-01-05 | — | — | US | disclosed |
| US-9227986-B2 | Diarylethene compounds and uses thereof | SWITCH MATERIALS, INC. (CA) | 2016-01-05 | — | — | US | disclosed |
| US-20140256936-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | SWITCH MATERIALS, INC. (CA) | 2014-09-11 | — | — | US | disclosed |
| US-20140256936-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | SWITCH MATERIALS, INC. (CA) | 2014-09-11 | — | — | US | disclosed |
| US-20140256936-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | SWITCH MATERIALS, INC. (CA) | 2014-09-11 | — | — | US | disclosed |
| EP-2760969-A1 | PHOTOCHROMIC AND ELECTROCHROMIC DIARYLCYCLOPENTENE DERIVATIVES AS OPTICAL FILTERS | Switch Materials, Inc. (CA) | 2014-08-06 | — | — | EP | disclosed |
| WO-2013044371-A1 | PHOTOCHROMIC AND ELECTROCHROMIC DIARYLCYCLOPENTENE DERIVATIVES AS OPTICAL FILTERS | SWITCH MATERIALS, INC. (CA) | 2013-04-04 | — | — | WO | disclosed |
| WO-2013044371-A1 | PHOTOCHROMIC AND ELECTROCHROMIC DIARYLCYCLOPENTENE DERIVATIVES AS OPTICAL FILTERS | SWITCH MATERIALS, INC. (CA) | 2013-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190256526-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | KCNH2, KCNH3, SCN2B | NPC1 3796/4885MAPT 4557/4885ALDH1A1 1014/4885 |
| US-10556912-B2 | Diarylethene compounds and uses thereof | KCNH2, KCNH3, SCN2B | NPC1 3796/4885MAPT 4557/4885ALDH1A1 1014/4885 |
| US-11124524-B2 | Diarylethene compounds and uses thereof | KCNH2, KCNH3, SCN2B | NPC1 3796/4885MAPT 4557/4885ALDH1A1 1014/4885 |
| US-20180339995-A1 | PHOTOCHROMIC AND ELECTROCHROMIC DIARYLCYCLOPENTENE DERIVATIVES AS OPTICAL FILTERS | HCN2, KCNH2, KCNH3 | NPC1 3464/4885MAPT 4716/4885ALDH1A1 939/4885 |
| US-20140256936-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | KCNH2, KCNH3, SCN2B | NPC1 3796/4885MAPT 4557/4885ALDH1A1 1014/4885 |
| US-20160083398-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | KCNH2, KCNH3, SCN2B | NPC1 3796/4885MAPT 4557/4885ALDH1A1 1014/4885 |
| US-10072023-B2 | Diarylethene compounds and uses thereof | KCNH2, KCNH3, SCN2B | NPC1 3796/4885MAPT 4557/4885ALDH1A1 1014/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.