Acetic Acid

Acetic Acid

SCHEMBL14833100

C=CCn1ccnc1.CC(=O)O

nearest known ligand 0.52

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Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.52
TBXAS1 P24557 15/20 0.50
EGLN3 Q9H6Z9 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL1324817 0.89 TBXAS1 (0.54) ALDH1A1TBXAS1EGLN3
Lactic Acid SCHEMBL5098496 0.87 TBXAS1 (0.48) ALDH1A1TBXAS1EGLN3
Benzene SCHEMBL27671800 0.87 TBXAS1 (0.47) ALDH1A1TBXAS1EGLN3
SCHEMBL83887 0.87
SCHEMBL16371567 0.87 TBXAS1 (0.48) ALDH1A1TBXAS1EGLN3
Hydrochloric Acid SCHEMBL252185 0.85
SCHEMBL16101937 0.85
Iodide SCHEMBL534239 0.85
Bromide SCHEMBL625730 0.85
SCHEMBL16101936 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9352298-B2 Method for producing polymer particles, and polymer particles JSR CORPORATION (JP) 2016-05-31 US disclosed
US-9162999-B2 Catalytic conversion of cellulose to fuels and chemicals using boronic acids WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2015-10-20 US disclosed
US-20130316892-A1 METHOD FOR PRODUCING POLYMER PARTICLES, AND POLYMER PARTICLES JSR CORPORATION (JP) 2013-11-28 US disclosed
US-20130178617-A1 CATALYTIC CONVERSION OF CELLULOSE TO FUELS AND CHEMICALS USING BORONIC ACIDS WISCONSIN ALUMNI RESEARCH FOUNDATION 2013-07-11 US disclosed
WO-2013049424-A1 CATALYTIC CONVERSION OF CELLULOSE TO FUELS AND CHEMICALS USING BORONIC ACIDS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2013-04-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130178617-A1 CATALYTIC CONVERSION OF CELLULOSE TO FUELS AND CHEMICALS USING BORONIC ACIDS MGAM, CA2, CA6 ALDH1A1 3895/4885TBXAS1 4165/4885EGLN3 2605/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.