Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13209596 | 0.70 | HSD17B10 (0.45) | OPRM1HTR2CHTR2BALDH1A1 | |
| SCHEMBL20764919 | 0.70 | GSK3A (0.31) | OPRM1 | |
| SCHEMBL2366412 | 0.62 | ADRB1 (0.50) | HTR2AHTR2CALDH1A1 | |
| SCHEMBL2906559 | 0.61 | HSP90AA1 (0.58) | ALDH1A1DAO | |
| SCHEMBL29870917 | 0.60 | PARP1 (0.32) | ALDH1A1PARP1 | |
| SCHEMBL13160309 | 0.59 | ADRB1 (0.48) | HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL9079129 | 0.58 | OPRM1 (0.42) | OPRM1HTR2C | |
| SCHEMBL16834276 | 0.58 | MEN1 (0.39) | HTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL3619375 | 0.58 | SMN1; SMN2 (0.52) | ALDH1A1 | |
| SCHEMBL17432211 | 0.57 | HTR2C (0.42) | HTR2AHTR2CHTR2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2576554-A1 | 1, 8 -DIAZASPIRO [4.5]DECANE- 2, 4 -DIONE DERIVATIVES USEFUL AS PESTICIDES | Syngenta Participations AG (CH) | 2013-04-10 | — | — | EP | disclosed |
| WO-2011151197-A1 | 1, 8 -DIAZASPIRO [4.5] DECANE- 2, 4 -DIONE DERIVATIVES USEFUL AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-08 | — | — | WO | disclosed |