Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 3/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.52 |
| ▸ | RHEB | Q15382 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | CBFB | Q13951 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1100174 | 0.80 | GRIN1 (0.70) | GRIN1GRIN2BGAANPC1RAB9A | |
| SCHEMBL20685279 | 0.75 | TYK2 (0.45) | NPC1RAB9A | |
| SCHEMBL14837228 | 0.74 | GRIN1 (0.48) | GRIN1GRIN2BRHEBMPOGAA | |
| SCHEMBL12066588 | 0.73 | MLKL (0.40) | CBFB | |
| SCHEMBL12066030 | 0.72 | PDE2A (0.38) | CBFBHCRTR1HCRTR2 | |
| SCHEMBL7001717 | 0.72 | CHEK1 (0.49) | GRIN1GRIN2BGAANPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6999319 | 0.71 | GAA (0.51) | GRIN1GRIN2BGAANPC1ALDH1A1 | |
| SCHEMBL4270442 | 0.70 | EGLN1 (0.42) | GAANPC1RAB9ACACNA1H | |
| SCHEMBL17308357 | 0.70 | DDAH1 (0.53) | GAANPC1ALDH1A1RAB9AHTR6 | |
| SCHEMBL5744116 | 0.70 | EGLN1 (0.42) | GRIN1GRIN2BGAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2578573-A1 | FUSED IMIDAZOLE DERIVATIVE | TOA Eiyo Ltd. (JP) | 2013-04-10 | — | — | EP | claimed |
| EP-2578573-A1 | FUSED IMIDAZOLE DERIVATIVE | TOA Eiyo Ltd. (JP) | 2013-04-10 | — | — | EP | disclosed |
| EP-2578573-A1 | FUSED IMIDAZOLE DERIVATIVE | TOA Eiyo Ltd. (JP) | 2013-04-10 | — | — | EP | disclosed |