Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | HTR2A | P28223 | 2/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | PKLR | P30613 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1711115 | 0.85 | PKM (0.85) | PKMMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL16015073 | 0.84 | GLA (0.51) | ALDH1A1L3MBTL1POLBLMNATSHR | |
| SCHEMBL4003126 | 0.84 | USP2 (0.48) | PKMMEN1KMT2AHTR2AHTR2C | |
| SCHEMBL2557643 | 0.81 | PKM (0.58) | PKMMEN1KMT2AHTR2AHTR2C | |
| SCHEMBL3236916 | 0.81 | MAPT (0.80) | PKMMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL423283 | 0.81 | MAPT (0.74) | PKMMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL17290485 | 0.81 | ALDH1A1 (0.45) | PKMMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL4009686 | 0.80 | CYP2D6 (0.49) | PKMMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL7096080 | 0.79 | USP2 (0.80) | PKMMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL4554939 | 0.79 | USP2 (0.80) | PKMMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346819-B1 | NAPHTHYLACETIC ACIDS | HOFFMANN LA ROCHE (CH) | 2013-04-10 | — | — | EP | disclosed |