Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.60 |
| ▸ | CTSB | P07858 | 3/20 | 0.60 |
| ▸ | REN | P00797 | 1/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | CTSL | P07711 | 4/20 | 0.52 |
| ▸ | CTSS | P25774 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19586026 | 0.92 | REN (0.62) | CTSKCTSBRENCASP3CAPN1 | |
| SCHEMBL19586943 | 0.92 | REN (0.62) | CTSKCTSBRENCASP3CAPN1 | |
| SCHEMBL10722584 | 0.91 | CTSK (0.60) | CTSKCTSBRENCASP3CAPN1 | |
| SCHEMBL19606091 | 0.90 | CTSK (0.64) | CTSKCTSBRENCASP3CAPN1 | |
| SCHEMBL29530699 | 0.90 | CTSK (0.64) | CTSKCTSBRENCASP3CAPN1 | |
| SCHEMBL21786912 | 0.90 | REN (0.60) | CTSKCTSBRENCASP3CAPN1 | |
| SCHEMBL21786911 | 0.90 | REN (0.60) | CTSKCTSBRENCASP3CAPN1 | |
| SCHEMBL10720680 | 0.89 | CTSK (0.60) | CTSKCTSBRENCASP3CAPN1 | |
| SCHEMBL7300437 | 0.86 | REN (0.57) | CTSKCTSBRENCASP3CAPN1 | |
| SCHEMBL22758554 | 0.86 | CTSK (0.60) | CTSKCTSBRENCASP3CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013049382-A2 | BROAD-SPECTRUM ANTIVIRALS AGAINST 3C OR 3C-LIKE PROTEASES OF PICORNAVIRUS-LIKE SUPERCLUSTER: PICORNAVIRUSES, CALICIVIRUSES AND CORONAVIRUSES | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2013-04-04 | — | — | WO | disclosed |