Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.60 |
| ▸ | CTSB | P07858 | 1/20 | 0.60 |
| ▸ | REN | P00797 | 1/20 | 0.55 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.53 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | CTSL | P07711 | 2/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22758538 | 1.00 | CTSK (0.60) | CTSKCTSBRENCAPN1CAPN2 | |
| SCHEMBL25076209 | 0.88 | CASP3 (0.49) | CTSKCTSBRENCASP3CTSL | |
| SCHEMBL19586026 | 0.87 | REN (0.62) | CTSKCTSBRENCAPN1CASP3 | |
| SCHEMBL19586943 | 0.87 | REN (0.62) | CTSKCTSBRENCAPN1CASP3 | |
| SCHEMBL10722584 | 0.86 | CTSK (0.60) | CTSKCTSBRENCAPN1CASP3 | |
| SCHEMBL14838006 | 0.86 | CTSK (0.60) | CTSKCTSBRENCAPN1CASP3 | |
| SCHEMBL10720680 | 0.86 | CTSK (0.60) | CTSKCTSBRENCAPN1CASP3 | |
| SCHEMBL19606091 | 0.86 | CTSK (0.64) | CTSKCTSBRENCAPN1CASP3 | |
| SCHEMBL29530699 | 0.86 | CTSK (0.64) | CTSKCTSBRENCAPN1CASP3 | |
| SCHEMBL21786911 | 0.85 | REN (0.60) | CTSKCTSBRENCAPN1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020247665-A1 | PEPTIDOMIMETICS FOR THE TREATMENT OF CORONAVIRUS AND PICORNAVIRUS INFECTIONS | EMORY UNIVERSITY (US) | 2020-12-10 | — | — | WO | disclosed |