Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10035902 | 0.92 | ALOX5 (0.37) | MAPTALOX5MEN1KMT2AALDH1A1 | |
| SCHEMBL14838429 | 0.90 | THRB (0.38) | MAOAMAOBMAPTTHRBCYP1A1 | |
| SCHEMBL21291329 | 0.90 | THRB (0.38) | MAOAMAOBMAPTTHRBCYP1A1 | |
| SCHEMBL14838376 | 0.90 | THRB (0.38) | MAOAMAOBMAPTTHRBCYP1A1 | |
| SCHEMBL16024128 | 0.90 | THRB (0.38) | MAOAMAOBMAPTTHRBCYP1A1 | |
| SCHEMBL16011184 | 0.90 | THRB (0.38) | MAOAMAOBMAPTTHRBCYP1A1 | |
| SCHEMBL16021761 | 0.89 | MAPT (0.37) | MAOAMAOBMAPTPOLBTHRB | |
| SCHEMBL14833740 | 0.84 | THRB (0.35) | MAOAMAOBMAPTTHRBCYP1A1 | |
| SCHEMBL21695434 | 0.83 | ALOX5 (0.40) | ALOX5CNR1TSHR | |
| SCHEMBL14838381 | 0.81 | ESR1 (0.41) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013044371-A1 | PHOTOCHROMIC AND ELECTROCHROMIC DIARYLCYCLOPENTENE DERIVATIVES AS OPTICAL FILTERS | SWITCH MATERIALS, INC. (CA) | 2013-04-04 | — | — | WO | disclosed |