Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.37 |
| ▸ | APP | P05067 | 4/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14838430 | 0.92 | MAOA (0.35) | ALOX5ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL21695434 | 0.90 | ALOX5 (0.40) | ALOX5APPTP53ALOX15TSHR | |
| SCHEMBL10002013 | 0.88 | APP (0.45) | APPOPRD1IKBKBESR1ESR2 | |
| SCHEMBL16021760 | 0.86 | OPRD1 (0.41) | ALOX5APPOPRD1IKBKBESR1 | |
| SCHEMBL9965558 | 0.84 | EP300 (0.33) | ESR1ESR2 | |
| SCHEMBL10036359 | 0.82 | HSD17B1 (0.38) | ESR1ESR2ALDH1A1MAPTMEN1 | |
| SCHEMBL16011190 | 0.82 | APP (0.40) | ALOX5APPOPRD1IKBKBESR1 | |
| SCHEMBL14838514 | 0.81 | OPRD1 (0.39) | APPOPRD1IKBKBESR1ESR2 | |
| SCHEMBL9965654 | 0.80 | MAPT (0.32) | MAPTTP53PDGFRBKITSMN1; SMN2 | |
| SCHEMBL16024128 | 0.80 | THRB (0.38) | APPOPRD1IKBKBESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120044560-A9 | VARIABLE TRANSMITTANCE OPTICAL FILTER AND USES THEREOF | SWITCH MATERIALS, INC. (CA) | 2012-02-23 | — | — | US | disclosed |
| US-20100315693-A1 | VARIABLE TRANSMITTANCE OPTICAL FILTER AND USES THEREOF | SWITCH MATERIALS, INC. (CA) | 2010-12-16 | — | — | US | disclosed |