SCHEMBL14838621

SCHEMBL14838621

O=C1c2ccccc2-c2cc(I)ccc21

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.55
KMT2A Q03164 4/20 0.55
CDC25B P30305 1/20 0.55
PTPRC P08575 6/20 0.52
NPC1 O15118 6/20 0.52
RAB9A P51151 6/20 0.52
SMN1; SMN2 Q16637 5/20 0.52
LMNA P02545 4/20 0.52
MAPK1 P28482 4/20 0.52
S100A4 P26447 4/20 0.52
APAF1 O14727 3/20 0.52
HTT P42858 3/20 0.52
GALK1 P51570 3/20 0.52
BLM P54132 3/20 0.52
NPSR1 Q6W5P4 3/20 0.52
MAPT P10636 3/20 0.52
PLA2G1B P04054 3/20 0.52
ATG4B Q9Y4P1 3/20 0.52
THRB P10828 2/20 0.52
TDP2 O95551 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1795673 0.95 MEN1 (0.55) MEN1KMT2ACDC25BPTPRCNPC1
SCHEMBL6449287 0.93 MEN1 (0.57) MEN1KMT2ACDC25BPTPRCNPC1
SCHEMBL745377 0.91 PTPRC (0.59) MEN1KMT2ACDC25BPTPRCNPC1
SCHEMBL21224167 0.91 TGM2 (0.50) MEN1KMT2ACDC25BPTPRCNPC1
SCHEMBL25227687 0.88 PTPRC (0.39) MEN1KMT2APTPRCNPC1RAB9A
SCHEMBL27896043 0.88 PTPRC (0.39) MEN1KMT2APTPRCNPC1RAB9A
SCHEMBL1795929 0.85 TGM2 (0.50) MEN1KMT2APTPRCNPC1RAB9A
SCHEMBL16267346 0.85 MAOA (0.50) MEN1KMT2ACDC25BPTPRCNPC1
SCHEMBL1963896 0.80 S100A4 (0.50) MEN1KMT2APTPRCNPC1RAB9A
SCHEMBL6230979 0.78 TGM2 (0.41) MEN1KMT2APTPRCNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105294415-A Preparation method of 3-halogenated fluorenone compound YANTAI GEM CHEMICALS CO LTD 2016-02-03 CN disclosed
WO-2013045408-A1 SPIROBIFLUORENE COMPOUNDS FOR LIGHT EMITTING DEVICES SOLVAY SA (BE) 2013-04-04 WO disclosed
WO-2013045410-A1 SPIROBIFLUORENE COMPOUNDS FOR LIGHT EMITTING DEVICES SOLVAY SA (BE) 2013-04-04 WO disclosed