Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14839481 | 0.95 | EGFR (0.50) | KDM4EMAPK1SMN1; SMN2NPC1POLB | |
| SCHEMBL14839478 | 0.93 | KDM4E (0.53) | KDM4EMAPK1SMN1; SMN2NPC1POLB | |
| SCHEMBL10411854 | 0.89 | CYP1A2 (0.52) | MAPK1CYP1A2LMNARARARARB | |
| SCHEMBL477645 | 0.85 | CYP1A2 (0.57) | SMN1; SMN2CYP1A2LMNAMAPTALDH1A1 | |
| SCHEMBL477646 | 0.85 | CYP1A2 (0.57) | SMN1; SMN2CYP1A2LMNAMAPTALDH1A1 | |
| SCHEMBL477469 | 0.85 | CYP1A2 (0.57) | SMN1; SMN2CYP1A2LMNAMAPTALDH1A1 | |
| SCHEMBL477467 | 0.85 | CYP1A2 (0.57) | SMN1; SMN2CYP1A2LMNAMAPTALDH1A1 | |
| SCHEMBL4630868 | 0.84 | CYP3A4 (0.51) | RAB9AEGFRCYP1A2KMT2AMAPT | |
| SCHEMBL4630867 | 0.84 | CYP3A4 (0.51) | RAB9AEGFRCYP1A2KMT2AMAPT | |
| SCHEMBL28403553 | 0.81 | ALOX15 (0.50) | KDM4ESMN1; SMN2NPC1RAB9AEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2775996-B1 | USE OF PROPANOL AND PROPENOL DERIVATIVES AS ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2018-02-28 | — | — | EP | disclosed |
| US-20150051295-A1 | USE OF PROPANOL AND PROPENOL DERIVATIVES AS ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2015-02-19 | — | — | US | disclosed |
| US-20150051295-A1 | USE OF PROPANOL AND PROPENOL DERIVATIVES AS ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2015-02-19 | — | — | US | disclosed |
| WO-2013045098-A2 | USE OF PROPANOL AND PROPENOL DERIVATIVES AS ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2013-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150051295-A1 | USE OF PROPANOL AND PROPENOL DERIVATIVES AS ANTIOXIDANTS | GPX4, EBP, CAT | KDM4E 3888/4885MAPK1 3467/4885SMN1; SMN2 3840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.