Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14805294 | 0.84 | SMN1; SMN2 (0.38) | LTA4HMEN1KMT2AGAAHDAC3 | |
| SCHEMBL4615305 | 0.82 | NR1H4 (0.56) | PAX8NR1H4MEN1KMT2AGAA | |
| SCHEMBL8018111 | 0.80 | PAX8 (0.55) | PAX8MEN1KMT2AGAALMNA | |
| SCHEMBL7531272 | 0.79 | PAX8 (0.50) | PAX8NR1H4MEN1KMT2AGAA | |
| SCHEMBL16197281 | 0.79 | PAX8 (0.50) | PAX8NR1H4MEN1KMT2AGAA | |
| SCHEMBL14798482 | 0.79 | LTA4H (0.37) | LTA4HMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL13674397 | 0.78 | PAX8 (0.49) | PAX8NR1H4MEN1KMT2AGAA | |
| SCHEMBL14090333 | 0.78 | PAX8 (0.49) | PAX8NR1H4MEN1KMT2AGAA | |
| SCHEMBL25960281 | 0.78 | PAX8 (0.49) | PAX8NR1H4MEN1KMT2AGAA | |
| SCHEMBL16856539 | 0.78 | PAX8 (0.49) | PAX8NR1H4MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013045280-A1 | DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2013-04-04 | — | — | WO | disclosed |