Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15986841 | 0.78 | TSHR (0.65) | ATMLMNASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL6555426 | 0.74 | ALDH1A1 (0.80) | ATMLMNASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL1483637 | 0.74 | HDAC1 (0.50) | LMNASMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL9921691 | 0.73 | ATM (0.76) | ATMLMNASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL13025526 | 0.72 | ATM (0.74) | ATMLMNASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL403057 | 0.72 | ATM (0.74) | ATMLMNASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL3216808 | 0.72 | ATM (0.74) | ATMLMNASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL10122851 | 0.71 | LMNA (1.00) | ATMLMNASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL22793764 | 0.71 | ATM (0.68) | ATMLMNASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL8338968 | 0.71 | HRH3 (0.73) | ATMLMNASMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8314103-B2 | Pyridyl derivatives, their preparation and use | Piramal Enterprises Limited (IN) | 2012-11-20 | — | — | US | disclosed |
| US-20110077252-A1 | PYRIDYL DERIVATIVES, THEIR PREPARATION AND USE | Piramal Enterprises Limited (IN) | 2011-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110077252-A1 | PYRIDYL DERIVATIVES, THEIR PREPARATION AND USE | HIF1AN, HIF1A, MTOR | ATM 605/4885LMNA 1638/4885SMN1; SMN2 3664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.