SCHEMBL1484068

SCHEMBL1484068

[CH2]C(C)CC(C)CC(C)C

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPK1 P28482 1/20 0.35
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
NFKB1 P19838 1/20 0.33
THPO P40225 1/20 0.33
GMNN O75496 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
PMP22 Q01453 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3246553 0.97 TSHR (0.33) TSHRALDH1A1MAPK1CYP3A4CYP2D6
SCHEMBL5984673 0.89
SCHEMBL10537874 0.82
SCHEMBL56255 0.82
SCHEMBL599901 0.82 TSHR (0.47) TSHRALDH1A1MAPK1CYP3A4CYP2D6
SCHEMBL23846021 0.78 TSHR (0.44) TSHRALDH1A1MAPK1CYP3A4CYP2D6
SCHEMBL31380967 0.78 TSHR (0.44) TSHRALDH1A1MAPK1CYP3A4CYP2D6
SCHEMBL17274592 0.78 TSHR (0.44) TSHRALDH1A1MAPK1CYP3A4CYP2D6
SCHEMBL19819960 0.78 TSHR (0.44) TSHRALDH1A1MAPK1CYP3A4CYP2D6
SCHEMBL8612234 0.75 TSHR (0.32) TSHRALDH1A1MAPK1CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10202322-B2 Resorcinol derivatives SUTTER BAY HOSPITALS (US) 2019-02-12 US claimed
US-20180170846-A1 RESORCINOL DERIVATIVES SUTTER WEST BAY HOSPITALS 2018-06-21 US claimed
US-20130209483-A1 CANNABIDINOID DERIVATIVES SUTTER WEST BAY HOSPITALS (US) 2013-08-15 US claimed
US-20090203699-A1 AMINOMETHYLPYRIDINE DERIVATIVES, METHOD FOR PREPARING SAME AND THERAPEUTIC USE THEREOF SANOFI-AVENTIS 2009-08-13 US claimed
CN-101421240-A Aminomethylpyridine derivatives, their preparation and use in therapy SANOFI AVENTIS (FR) 2009-04-29 CN claimed
EP-2010492-A2 AMINOMETHYL PYRIDINE DERIVATIVES, METHOD FOR PREPARING SAME AND THERAPEUTIC USE THEREOF Sanofi-Aventis (FR) 2009-01-07 EP claimed
WO-2007119001-A2 AMINOMETHYL PYRIDINE DERIVATIVES, METHOD FOR PREPARING SAME AND THERAPEUTIC USE THEREOF SANOFI-AVENTIS (FR) 2007-10-25 WO claimed
US-4301083-A BY REACTION WITH AN ORGANIC CHLORIDE OR BROMIDE IN THE PRESENCE OF SODIUM OR POTASSIUM HYDROXIDE KURARAY CO., LTD. (JP) 1981-11-17 US claimed
US-12037660-B2 Use of synergistic mixture of extractants for extracting rare earth elements from an aqueous medium comprising phosphoric acid Commissariat à l'énergie atomique et aux énergies alternatives (FR) 2024-07-16 US disclosed
CN-115885026-B Viscosity index improver composition and lubricating oil composition 三洋化成工业株式会社 2024-06-21 CN disclosed
WO-2024056517-A1 USE OF AN ALKYLETHER SULFATE FOR IMPROVING THE EFFICACY OF HERBICIDES BASF SE (DE) 2024-03-21 WO disclosed
CN-113396144-B Polymer compound and method for producing same, composition and method for producing same, resin composition, additive for lubricating oil, and lubricating oil 三菱化学株式会社 2024-01-12 CN disclosed
CN-117098788-A Resin composition, film and copolymer 住友化学株式会社 2023-11-21 CN disclosed
US-20230340357-A1 VISCOSITY INDEX IMPROVER COMPOSITION AND LUBRICATING OIL COMPOSITION SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2023-10-26 US disclosed
EP-0423764-A2 Silver halide colour photographic material and cyan coupler of the 2-phenylureido-5-acylaminophenol type FUJI PHOTO FILM CO., LTD. (JP) 1991-04-24 EP disclosed
EP-0083311-B1 2,3-DIHYDROPERIMIDINES AS ANTIOXIDANTS FOR LUBRICANTS CIBA-GEIGY AG (CH) 1986-08-13 EP disclosed
EP-0083311-A2 2,3-Dihydroperimidines as antioxidants for lubricants CIBA-GEIGY AG (CH) 1983-07-06 EP disclosed
US-4389321-A 2,3-Dihydroperimidines as antioxidants for lubricants CIBA-GEIGY CORPORATION (US) 1983-06-21 US disclosed
US-4301083-A BY REACTION WITH AN ORGANIC CHLORIDE OR BROMIDE IN THE PRESENCE OF SODIUM OR POTASSIUM HYDROXIDE KURARAY CO., LTD. (JP) 1981-11-17 US disclosed
US-3956408-A CARBON MONOXIDE, METAL SALT CATALYST ETHYL CORPORATION (US) 1976-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090203699-A1 AMINOMETHYLPYRIDINE DERIVATIVES, METHOD FOR PREPARING SAME AND THERAPEUTIC USE THEREOF TPMT, QDPR, HNMT TSHR 4190/4885ALDH1A1 388/4885MAPK1 4344/4885
US-10202322-B2 Resorcinol derivatives CNR1, CNR2, RCOR1 TSHR 3290/4885ALDH1A1 1955/4885MAPK1 3453/4885
US-20130209483-A1 CANNABIDINOID DERIVATIVES CNR2, CNR1, GPR18 TSHR 4095/4885ALDH1A1 3491/4885MAPK1 3372/4885
US-20180170846-A1 RESORCINOL DERIVATIVES CNR1, CNR2, RCOR1 TSHR 3290/4885ALDH1A1 1955/4885MAPK1 3453/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.