SCHEMBL14842017

SCHEMBL14842017

CCCc1ccccc1-c1ccc(S(=O)(=O)O)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 2/20 0.47
TSHR P16473 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
PTGS2 P35354 4/20 0.42
BRD4 O60885 1/20 0.40
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
TYMS P04818 1/20 0.39
LTB4R2 Q9NPC1 1/20 0.39
POLB P06746 1/20 0.39
CYP2D6 P10635 1/20 0.39
SLC6A2 P23975 1/20 0.38
DRD1 P21728 2/20 0.38
LMNA P02545 1/20 0.37
PTGER1 P34995 1/20 0.37
PTGER4 P35408 1/20 0.37
PTGER3 P43115 1/20 0.37
PTGER2 P43116 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL14842093 0.98 PPARA (0.46) PPARATSHRSMN1; SMN2PTGS2BRD4
SCHEMBL3395182 0.91 PPARA (0.45) PPARATSHRSMN1; SMN2PTGS2CA12
SCHEMBL28295855 0.83 PPARA (0.49) PPARASMN1; SMN2PTGS2CA12CA1
SCHEMBL14842018 0.81 CA2 (0.40) PPARATSHRSMN1; SMN2PTGS2CA1
Water SCHEMBL14842096 0.80 CA2 (0.40) PPARATSHRSMN1; SMN2PTGS2CA1
SCHEMBL3235687 0.80 SLC6A2 (0.41) TSHRSMN1; SMN2PTGS2CA12CA1
Bicarbonate SCHEMBL1835067 0.78 PPARA (0.56) PPARACA12CA1CA2CA9
SCHEMBL4383694 0.78 PPARA (0.49) PPARALTB4R2PTGER1PTGER4PTGER3
SCHEMBL10798302 0.77 DPP4 (0.52) PPARASMN1; SMN2CA12CA1CA2
SCHEMBL607543 0.77 DPP4 (0.56) PPARASMN1; SMN2CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140296485-A1 ANIONIC DISPLACER MOLECULES FOR HYDROPHOBIC DISPLACEMENT CHROMATOGRAPHY PNC BANK, NATIONAL ASSOCIATION 2014-10-02 US disclosed
EP-2763772-A2 ANIONIC DISPLACER MOLECULES FOR HYDROPHOBIC DISPLACEMENT CHROMATOGRAPHY Sachem, Inc. (US) 2014-08-13 EP disclosed
WO-2013052537-A2 ANIONIC DISPLACER MOLECULES FOR HYDROPHOBIC DISPLACEMENT CHROMATOGRAPHY SACHEM, INC. (US) 2013-04-11 WO disclosed