Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL14842096 | 0.98 | CA2 (0.40) | CA2CA1CA9PTGS2FBP1 | |
| SCHEMBL30513622 | 0.85 | CA2 (0.52) | CA2CA1CA9PTGS2 | |
| SCHEMBL27755329 | 0.85 | TSHR (0.40) | PTGS2FBP1TSHRSMN1; SMN2HDAC6 | |
| SCHEMBL14842017 | 0.81 | PPARA (0.47) | CA2CA1CA9PTGS2TSHR | |
| Water SCHEMBL14842093 | 0.80 | PPARA (0.46) | CA2CA1CA9PTGS2TSHR | |
| SCHEMBL11403365 | 0.79 | ALDH1A1 (0.40) | CA2CA1TSHRSMN1; SMN2SNCA | |
| SCHEMBL28295855 | 0.78 | PPARA (0.49) | CA2CA1CA9PTGS2SMN1; SMN2 | |
| SCHEMBL5305256 | 0.77 | TSHR (0.52) | PTGS2TSHRSMN1; SMN2HDAC6PTGDR2 | |
| SCHEMBL6053296 | 0.77 | ALOX5 (0.55) | CA2CA1CA9PTGS2TSHR | |
| SCHEMBL4629945 | 0.76 | MAPT (0.39) | CA2CA1CA9PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140296485-A1 | ANIONIC DISPLACER MOLECULES FOR HYDROPHOBIC DISPLACEMENT CHROMATOGRAPHY | PNC BANK, NATIONAL ASSOCIATION | 2014-10-02 | — | — | US | disclosed |
| EP-2763772-A2 | ANIONIC DISPLACER MOLECULES FOR HYDROPHOBIC DISPLACEMENT CHROMATOGRAPHY | Sachem, Inc. (US) | 2014-08-13 | — | — | EP | disclosed |
| WO-2013052537-A2 | ANIONIC DISPLACER MOLECULES FOR HYDROPHOBIC DISPLACEMENT CHROMATOGRAPHY | SACHEM, INC. (US) | 2013-04-11 | — | — | WO | disclosed |