SCHEMBL14844445

SCHEMBL14844445

C=Cc1ccc(C(=O)C(=O)OC2(C)CCCCC2)cc1

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.39
TAS1R3 Q7RTX0 3/20 0.36
TAS1R1 Q7RTX1 3/20 0.36
RARA P10276 3/20 0.34
RARB P10826 3/20 0.34
RARG P13631 3/20 0.34
ALDH1A1 P00352 2/20 0.31
HDAC3 O15379 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17247256 0.85 CYP19A1 (0.40) CYP19A1TAS1R3TAS1R1RARARARB
SCHEMBL14527796 0.84 CYP19A1 (0.38) CYP19A1TAS1R3TAS1R1RARARARB
SCHEMBL23929398 0.80 CYP19A1 (0.43) CYP19A1ALDH1A1
4-Vinylphenol SCHEMBL28670504 0.78 CYP19A1 (0.35) CYP19A1RARARARBRARGALDH1A1
SCHEMBL17247246 0.78 THRB (0.38) CYP19A1ALDH1A1
SCHEMBL17247233 0.76 PTGS2 (0.36) CYP19A1ALDH1A1
SCHEMBL9626757 0.74 CYP19A1 (0.45) CYP19A1ALDH1A1
SCHEMBL9626667 0.73 CYP19A1 (0.36) CYP19A1TAS1R3TAS1R1ALDH1A1
SCHEMBL19349431 0.73 TAS1R3 (0.49) TAS1R3TAS1R1ALDH1A1TDP1
SCHEMBL9627685 0.72 CYP19A1 (0.43) CYP19A1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2748208-A1 PHOTOLABILE LATEX FOR THE RELEASE OF PERFUMES Firmenich SA (CH) 2014-07-02 EP disclosed
WO-2013050303-A1 PHOTOLABILE LATEX FOR THE RELEASE OF PERFUMES FIRMENICH SA (CH) 2013-04-11 WO disclosed