Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | BCAT1 | P54687 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | BCAT2 | O15382 | 3/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14844553 | 0.83 | KDM4E (0.33) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL14844997 | 0.72 | ALDH1A1 (0.33) | ALDH1A1HPGDLRRK2PRMT5WDR77 | |
| SCHEMBL16716788 | 0.71 | ALDH1A1 (0.35) | ALDH1A1KDM4EMAPTHPGDLRRK2 | |
| SCHEMBL16716787 | 0.68 | ALDH1A1 (0.36) | ALDH1A1HPGDLRRK2 | |
| SCHEMBL16716785 | 0.67 | ALDH1A1 (0.37) | ALDH1A1HPGDLRRK2 | |
| SCHEMBL14844488 | 0.67 | RAB9A (0.39) | ALDH1A1LMNAMAPTHPGDLRRK2 | |
| SCHEMBL16716777 | 0.66 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGD | |
| SCHEMBL14844564 | 0.65 | ALDH1A1 (0.39) | ALDH1A1HPGD | |
| SCHEMBL14844550 | 0.65 | ALDH1A1 (0.36) | ALDH1A1HPGDLRRK2 | |
| SCHEMBL14844339 | 0.64 | ALOX5AP (0.43) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2763968-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | Syngenta Limited (GB) | 2014-08-13 | — | — | EP | disclosed |
| WO-2013050421-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | SYNGENTA LIMITED (GB) | 2013-04-11 | — | — | WO | disclosed |