Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 7/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | TTK | P33981 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16716785 | 0.80 | ALDH1A1 (0.37) | ALDH1A1HPGDLRRK2ARTRPA1 | |
| SCHEMBL16716777 | 0.79 | ALDH1A1 (0.41) | ALDH1A1HPGDNPBWR1 | |
| SCHEMBL14844550 | 0.78 | ALDH1A1 (0.36) | ALDH1A1HPGDLRRK2TRPA1 | |
| SCHEMBL16716788 | 0.77 | ALDH1A1 (0.35) | ALDH1A1HPGDLRRK2ARTRPA1 | |
| SCHEMBL14844488 | 0.72 | RAB9A (0.39) | ALDH1A1HPGDLRRK2NPBWR1CYP11B2 | |
| SCHEMBL14844412 | 0.72 | ALDH1A1 (0.35) | ALDH1A1HPGDLRRK2PDE10A | |
| SCHEMBL16719163 | 0.71 | NPBWR1 (0.40) | ALDH1A1AURKAKDRAURKBNPBWR1 | |
| SCHEMBL23152444 | 0.70 | LRRK2 (0.34) | ALDH1A1HPGDLRRK2 | |
| SCHEMBL29464822 | 0.70 | LRRK2 (0.34) | ALDH1A1HPGDLRRK2 | |
| SCHEMBL14844564 | 0.70 | ALDH1A1 (0.39) | ALDH1A1HPGDNPBWR1HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068773-B1 | PYRIDAZINONE DERIVATIVES AND THEIR USE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2017-07-05 | — | — | EP | disclosed |
| US-20160272613-A1 | Pyridazinone Derivatives and their use as Herbicides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-09-22 | — | — | US | disclosed |
| EP-3068773-A1 | PYRIDAZINONE DERIVATIVES AND THEIR USE AS HERBICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015071205-A1 | PYRIDAZINONE DERIVATIVES AND THEIR USE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2015-05-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160272613-A1 | Pyridazinone Derivatives and their use as Herbicides | PDXK, CBR3, DDT | ALDH1A1 240/4885HPGD 301/4885LRRK2 4214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.