SCHEMBL14844963

SCHEMBL14844963

N#CCCOc1ccc(C(=O)O)cc1

nearest known ligand 0.62

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ PKM P14618 1/20 0.62
▸ MAPK1 P28482 2/20 0.56
▸ TSHR P16473 2/20 0.56
▸ TP53 P04637 1/20 0.56
▸ PLA2G4B P0C869 5/20 0.54
▸ ALDH1A1 P00352 2/20 0.54
▸ L3MBTL1 Q9Y468 1/20 0.54
▸ USP2 O75604 1/20 0.53
▸ ALOX15 P16050 1/20 0.53
▸ HSD17B10 Q99714 1/20 0.53
▸ GAA P10253 1/20 0.51
▸ RARB P10826 4/20 0.51
▸ HTT P42858 1/20 0.51
▸ MAPT P10636 1/20 0.50
▸ NR4A1 P22736 1/20 0.50
▸ NR4A2 P43354 1/20 0.50
▸ NR4A3 Q92570 1/20 0.50
▸ PLA2G4A P47712 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7239214 0.91 PKM (0.61) PKMMAPK1TSHRTP53PLA2G4B
SCHEMBL14844080 0.90 TP53 (0.61) PKMMAPK1TSHRTP53PLA2G4B
SCHEMBL196110 0.82 PKM (0.88) PKMMAPK1TSHRTP53PLA2G4B
SCHEMBL11767977 0.82 GAA (0.68) ALDH1A1GAAMAPT
SCHEMBL25375924 0.82 PKM (0.62) PKMMAPK1TSHRTP53PLA2G4B
SCHEMBL30172106 0.81 PKM (0.56) PKMMAPK1TSHRTP53PLA2G4B
SCHEMBL1952122 0.81 TP53 (0.79) PKMMAPK1TSHRTP53PLA2G4B
SCHEMBL118037 0.81 PKM (0.77) PKMMAPK1TSHRTP53PLA2G4B
SCHEMBL5434949 0.79 PKM (0.59) PKMMAPK1TSHRTP53PLA2G4B
SCHEMBL7911508 0.79 TP53 (0.82) PKMTSHRTP53PLA2G4BALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118027412-A Photo-alignment material 罗利克技术有限公司 2024-05-14 — — CN disclosed
US-11634544-B2 Photoaligning materials Rolic Technologies AG (CH) 2023-04-25 — — US disclosed
US-20210340330-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2021-11-04 — — US disclosed
CN-108912011-B Photoalignment material 罗立克科技股份公司 2021-09-24 — — CN disclosed
US-20200223984-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2020-07-16 — — US disclosed
US-10696795-B2 Photoaligning materials Rolic Technologies AG (CH) 2020-06-30 — — US disclosed
EP-2936244-B1 METHOD FOR THE PLANAR PHOTOALIGNMENT ROLIC TECH AG (CH) 2019-07-10 — — EP disclosed
US-20180319939-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2018-11-08 — — US disclosed
EP-3374416-A1 PHOTOALIGNMENT MATERIALS ROLIC Technologies AG (CH) 2018-09-19 — — EP disclosed
WO-2017081056-A1 PHOTOALIGNMENT MATERIALS ROLIC AG (CH) 2017-05-18 — — WO disclosed
US-9493394-B2 Photoaligning materials ROLIC AG (CH) 2016-11-15 — — US disclosed
US-9334366-B2 Photoaligning materials ROLIC AG (CH) 2016-05-10 — — US disclosed
EP-2936244-A1 METHOD FOR THE PLANAR PHOTOALIGNMENT Rolic AG (CH) 2015-10-28 — — EP disclosed
US-20140342086-A1 PHOTOALIGNING MATERIALS ROLIC AG (CH) 2014-11-20 — — US disclosed
US-20140249244-A1 PHOTOALIGNING MATERIALS ROLIC AG (CH) 2014-09-04 — — US disclosed
EP-2763958-A1 PHOTOALIGNING MATERIALS Rolic AG (CH) 2014-08-13 — — EP disclosed
EP-2763957-A1 PHOTOALIGNING MATERIALS Rolic AG (CH) 2014-08-13 — — EP disclosed
WO-2014095414-A1 METHOD FOR THE PLANAR PHOTOALIGNMENT ROLIC AG (CH) 2014-06-26 — — WO disclosed
WO-2013050121-A1 PHOTOALIGNING MATERIALS ROLIC AG (CH) 2013-04-11 — — WO disclosed
WO-2013050122-A1 PHOTOALIGNING MATERIALS ROLIC AG (CH) 2013-04-11 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140249244-A1 PHOTOALIGNING MATERIALS LCP1, PIN1, MAP1LC3C PKM 2172/4885MAPK1 699/4885TSHR 4833/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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