Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | PLA2G4B | P0C869 | 7/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | RARB | P10826 | 5/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14844080 | 0.95 | TP53 (0.61) | PKMMAPK1TSHRTP53PLA2G4B | |
| SCHEMBL14844963 | 0.91 | PKM (0.62) | PKMMAPK1TSHRTP53PLA2G4B | |
| SCHEMBL14843854 | 0.85 | ALDH1A1 (0.56) | PKMMAPK1TSHRTP53PLA2G4B | |
| SCHEMBL14843851 | 0.85 | ALDH1A1 (0.56) | PKMMAPK1TSHRTP53PLA2G4B | |
| SCHEMBL28595106 | 0.84 | XDH (0.53) | PKMALDH1A1RARBHSD17B10 | |
| SCHEMBL118037 | 0.83 | PKM (0.77) | PKMMAPK1TSHRTP53PLA2G4B | |
| SCHEMBL1952122 | 0.83 | TP53 (0.79) | PKMMAPK1TSHRTP53PLA2G4B | |
| SCHEMBL24000908 | 0.83 | PKM (0.61) | PKMMAPK1TSHRTP53PLA2G4B | |
| SCHEMBL28114029 | 0.82 | MAPT (0.54) | PKMTSHR | |
| SCHEMBL209561 | 0.81 | TP53 (0.82) | PKMTSHRTP53PLA2G4BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108329282-B | Phenylpiperazine derivative and preparation method and application thereof | 新乡医学院 | 2022-01-07 | — | — | CN | disclosed |
| EP-2936244-B1 | METHOD FOR THE PLANAR PHOTOALIGNMENT | ROLIC TECH AG (CH) | 2019-07-10 | — | — | EP | disclosed |
| CN-109804306-A | Light orientation copolymer material | 罗利克技术有限公司 | 2019-05-24 | — | — | CN | disclosed |
| US-9493394-B2 | Photoaligning materials | ROLIC AG (CH) | 2016-11-15 | — | — | US | disclosed |
| US-9493394-B2 | Photoaligning materials | ROLIC AG (CH) | 2016-11-15 | — | — | US | disclosed |
| US-9334366-B2 | Photoaligning materials | ROLIC AG (CH) | 2016-05-10 | — | — | US | disclosed |
| US-9334366-B2 | Photoaligning materials | ROLIC AG (CH) | 2016-05-10 | — | — | US | disclosed |
| US-20140342086-A1 | PHOTOALIGNING MATERIALS | ROLIC AG (CH) | 2014-11-20 | — | — | US | disclosed |
| US-20140342086-A1 | PHOTOALIGNING MATERIALS | ROLIC AG (CH) | 2014-11-20 | — | — | US | disclosed |
| US-20140249244-A1 | PHOTOALIGNING MATERIALS | ROLIC AG (CH) | 2014-09-04 | — | — | US | disclosed |
| US-20140249244-A1 | PHOTOALIGNING MATERIALS | ROLIC AG (CH) | 2014-09-04 | — | — | US | disclosed |
| WO-2014095414-A1 | METHOD FOR THE PLANAR PHOTOALIGNMENT | ROLIC AG (CH) | 2014-06-26 | — | — | WO | disclosed |
| WO-2013050121-A1 | PHOTOALIGNING MATERIALS | ROLIC AG (CH) | 2013-04-11 | — | — | WO | disclosed |
| WO-2013050122-A1 | PHOTOALIGNING MATERIALS | ROLIC AG (CH) | 2013-04-11 | — | — | WO | disclosed |
| US-6506747-B1 | Method of treating an inflammatory disease which comprises administering to a patient in need of such treatment-a N-(4-(5-Ethyl-3-pyridin-3-yl-pyrazol-1-yl)phenyl)pyridine-3-carboxamide; | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2003-01-14 | — | — | US | disclosed |
| WO-1999062885-A1 | SUBSTITUTED 1-(4-AMINOPHENYL)PYRAZOLES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1999-12-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140249244-A1 | PHOTOALIGNING MATERIALS | LCP1, PIN1, MAP1LC3C | PKM 2172/4885MAPK1 699/4885TSHR 4833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.