Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | CES2 | O00748 | 2/20 | 0.60 |
| ▸ | CES1 | P23141 | 2/20 | 0.60 |
| ▸ | CA1 | P00915 | 6/20 | 0.48 |
| ▸ | CA2 | P00918 | 6/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.47 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14845458 | 0.89 | CES2 (0.75) | MAPTCES2CES1CA1CA2 | |
| SCHEMBL2419348 | 0.83 | MAPT (1.00) | MAPTCES2CES1CA1CA2 | |
| SCHEMBL14845429 | 0.80 | ELANE (0.53) | MAPTCES2CES1RAB9ANPSR1 | |
| SCHEMBL14845467 | 0.80 | CES2 (0.56) | MAPTCES2CES1CA1CA2 | |
| SCHEMBL31634553 | 0.80 | MAPT (0.57) | MAPTCES2CES1CA1CA2 | |
| SCHEMBL14845468 | 0.79 | MAPT (0.56) | MAPTCES2CES1CA1CA2 | |
| Dimethylamine SCHEMBL11023098 | 0.79 | MAPT (0.89) | MAPTCES2CES1CA1CA2 | |
| SCHEMBL14845456 | 0.78 | RAB9A (0.51) | MAPTCA2RAB9ANPC1CYP1A2 | |
| SCHEMBL14845435 | 0.78 | PLK1 (0.43) | MAPTRAB9ANPSR1NPC1CYP1A2 | |
| SCHEMBL2122107 | 0.77 | CES2 (0.75) | MAPTCES2CES1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8414982-B2 | Process for the production of strongly adherent coatings | BASF SE (DE) | 2013-04-09 | — | — | US | disclosed |