Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | CES2 | O00748 | 2/20 | 0.72 |
| ▸ | CES1 | P23141 | 2/20 | 0.72 |
| ▸ | CA1 | P00915 | 6/20 | 0.57 |
| ▸ | CA2 | P00918 | 6/20 | 0.57 |
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.55 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.55 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.55 |
| ▸ | PLK1 | P53350 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL11023098 | 0.94 | MAPT (0.89) | MAPTCES2CES1CA1CA2 | |
| SCHEMBL1322648 | 0.89 | MAPT (0.80) | MAPTCES2CES1CA1CA2 | |
| SCHEMBL5148119 | 0.85 | MAPT (0.73) | MAPTCES2CES1CA1CA2 | |
| SCHEMBL14507040 | 0.84 | CES2 (1.00) | MAPTCES2CES1CA1CA2 | |
| SCHEMBL557152 | 0.84 | CES2 (1.00) | MAPTCES2CES1CA1CA2 | |
| SCHEMBL28670034 | 0.84 | MAPT (0.71) | MAPTCES2CES1NPSR1MEN1 | |
| SCHEMBL14886374 | 0.84 | MAPT (0.72) | MAPTCES2CES1CA1CA2 | |
| SCHEMBL14845451 | 0.83 | MAPT (0.71) | MAPTCES2CES1CA1CA2 | |
| SCHEMBL18982976 | 0.83 | CES2 (0.72) | MAPTCES2CES1CA1CA2 | |
| SCHEMBL2320546 | 0.83 | CES2 (0.78) | MAPTCES2CES1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112592310-B | 2-hydroxypyridine compound and synthetic method thereof | 南京工业大学 | 2022-04-29 | — | — | CN | disclosed |
| US-9983490-B2 | Electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2018-05-29 | — | — | US | disclosed |
| US-9983490-B2 | Electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2018-05-29 | — | — | US | disclosed |
| US-9811012-B2 | Electrophotographic photosensitive member, process cartridge, electrophotographic apparatus and process for producing electrophotographic photosensitive member | CANON KABUSHIKI KAISHA (JP) | 2017-11-07 | — | — | US | disclosed |
| US-9811012-B2 | Electrophotographic photosensitive member, process cartridge, electrophotographic apparatus and process for producing electrophotographic photosensitive member | CANON KABUSHIKI KAISHA (JP) | 2017-11-07 | — | — | US | disclosed |
| US-20170285499-A1 | ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2017-10-05 | — | — | US | disclosed |
| US-20170285499-A1 | ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2017-10-05 | — | — | US | disclosed |
| US-20170090309-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, ELECTROPHOTOGRAPHIC APPARATUS AND PROCESS FOR PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | CANON KABUSHIKI KAISHA (JP) | 2017-03-30 | — | — | US | disclosed |
| US-20170090309-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, ELECTROPHOTOGRAPHIC APPARATUS AND PROCESS FOR PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | CANON KABUSHIKI KAISHA (JP) | 2017-03-30 | — | — | US | disclosed |
| EP-1257264-B1 | ESTROGEN RECEPTOR MODULATORS | MERCK SHARP & DOHME (US) | 2011-09-14 | — | — | EP | disclosed |
| US-7087599-B2 | Estrogen receptor modulators | MERCK & CO., INC. (US) | 2006-08-08 | — | — | US | disclosed |
| EP-1257264-A4 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO INC (US) | 2005-08-10 | — | — | EP | disclosed |
| US-20050137192-A1 | Estrogen receptor modulators | PARKER DANN R JR (US) | 2005-06-23 | — | — | US | disclosed |
| US-20030027840-A1 | Estrogen receptor modulators | MERCK SHARP & DOHME LLC | 2003-02-06 | — | — | US | disclosed |
| EP-1257264-A1 | ESTROGEN RECEPTOR MODULATORS | Merck & Co., Inc. (US) | 2002-11-20 | — | — | EP | disclosed |
| WO-2001082923-A1 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2001-11-08 | — | — | WO | disclosed |
| US-4983252-A | Process for producing printed circuit board | MITSUBISHI DENKI KABUSHIKI KAISHA (JP) | 1991-01-08 | — | — | US | disclosed |
| EP-0061689-B1 | RADIATION SENSITIVE POLYMER MATERIALS | Hitachi, Ltd. (JP) | 1986-08-27 | — | — | EP | disclosed |
| US-4419506-A | METHACRYLOPHENONE POLYMERS | HITACHI, LTD. (JP) | 1983-12-06 | — | — | US | disclosed |
| EP-0061689-A1 | Radiation sensitive polymer materials | Hitachi, Ltd. (JP) | 1982-10-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030027840-A1 | Estrogen receptor modulators | GPER1, ESR2, ESRRA | MAPT 1213/4885CES2 1598/4885CES1 205/4885 |
| US-20050137192-A1 | Estrogen receptor modulators | GPER1, ESR2, ESRRA | MAPT 1213/4885CES2 1598/4885CES1 205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.