Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSG | P08311 | 2/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.51 |
| ▸ | ITGAV | P06756 | 2/20 | 0.51 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.51 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.51 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.51 |
| ▸ | MC4R | P32245 | 8/20 | 0.50 |
| ▸ | MC5R | P33032 | 8/20 | 0.50 |
| ▸ | MC3R | P41968 | 8/20 | 0.50 |
| ▸ | MC1R | Q01726 | 8/20 | 0.50 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 2/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.46 |
| ▸ | TSLP | Q969D9 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15335358 | 0.96 | CTSG (0.50) | CTSGITGB3ITGAVITGB1ITGA5 | |
| SCHEMBL13656508 | 0.94 | MC4R (0.51) | CTSGITGB3ITGAVITGB1ITGA5 | |
| SCHEMBL13062248 | 0.94 | TSLP (0.49) | CTSGITGB3ITGAVITGB1ITGA5 | |
| SCHEMBL13014693 | 0.94 | CTSG (0.55) | CTSGITGB3ITGAVITGB1ITGA5 | |
| SCHEMBL16349774 | 0.94 | MC4R (0.51) | CTSGITGB3ITGAVITGB1ITGA5 | |
| SCHEMBL14962605 | 0.93 | MC4R (0.54) | CTSGITGB3ITGAVITGB1ITGA5 | |
| SCHEMBL14137295 | 0.93 | CTSG (0.54) | CTSGITGB3ITGAVITGB1ITGA5 | |
| SCHEMBL12361592 | 0.91 | MC4R (0.51) | CTSGITGB3ITGAVITGB1ITGA5 | |
| SCHEMBL12462669 | 0.91 | GRB7 (0.54) | CTSGITGB3ITGAVITGB1ITGA5 | |
| SCHEMBL20809943 | 0.91 | GRB7 (0.54) | CTSGITGB3ITGAVITGB1ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8415510-B2 | Synthesis of a PEG-6 moiety from commercial low-cost chemicals | GE HEALTHCARE LIMITED (GB) | 2013-04-09 | — | — | US | disclosed |