Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 3/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9676821 | 1.00 | GAA (0.59) | GAAMAPTKDM4ECA2HTR6 | |
| SCHEMBL14845761 | 0.84 | GAA (0.61) | GAAMAPTKDM4ECA2HTR6 | |
| SCHEMBL8149846 | 0.84 | CA2 (0.64) | GAAMAPTKDM4ECA2HTR6 | |
| SCHEMBL4889389 | 0.82 | GAA (0.59) | GAAMAPTKDM4ECA2HTR6 | |
| SCHEMBL17322787 | 0.82 | GAA (0.59) | GAAMAPTKDM4ECA2HTR6 | |
| SCHEMBL15631840 | 0.81 | GAA (0.57) | GAAMAPTKDM4ECA2HTR6 | |
| SCHEMBL10048751 | 0.81 | GAA (0.57) | GAAMAPTKDM4ECA2HTR6 | |
| SCHEMBL14142748 | 0.79 | GAA (0.55) | GAAMAPTKDM4ECA2HTR6 | |
| SCHEMBL15075265 | 0.79 | GAA (0.55) | GAAMAPTKDM4ECA2HTR6 | |
| SCHEMBL13677633 | 0.79 | MAPT (0.55) | GAAMAPTKDM4ECA2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023278826-A2 | METHODS FOR SELECTING LUNG CANCER PATIENTS FOR TREATMENT WITH NON-STEROIDAL ANTI-INFLAMMATORY DRUGS | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2023-01-05 | — | — | WO | disclosed |