Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 12/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | TNKS | O95271 | 5/20 | 0.52 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.52 |
| ▸ | PARP1 | P09874 | 2/20 | 0.52 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL297069 | 0.87 | GUSB (0.67) | GUSBHPGDKDM4ETNKSTNKS2 | |
| SCHEMBL1084872 | 0.81 | GUSB (0.78) | GUSBHPGDKDM4ETNKSTNKS2 | |
| SCHEMBL29740691 | 0.81 | GUSB (0.78) | GUSBHPGDKDM4ETNKSTNKS2 | |
| SCHEMBL13604403 | 0.81 | GUSB (0.69) | GUSBHPGDKDM4ETNKSTNKS2 | |
| SCHEMBL10205334 | 0.80 | GUSB (0.68) | GUSBHPGDKDM4ETNKSTNKS2 | |
| SCHEMBL4579539 | 0.80 | GUSB (0.67) | GUSBHPGDKDM4ETNKSTNKS2 | |
| SCHEMBL4579536 | 0.79 | GUSB (0.63) | GUSBHPGDKDM4ETNKSTNKS2 | |
| SCHEMBL7160589 | 0.77 | GUSB (1.00) | GUSBHPGDKDM4E | |
| SCHEMBL31238756 | 0.77 | GUSB (1.00) | GUSBHPGDKDM4E | |
| SCHEMBL4085196 | 0.77 | GUSB (0.60) | GUSBHPGDKDM4ETNKSTNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9605296-B2 | Fluorogenic peptidase substrate | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2017-03-28 | — | — | US | disclosed |
| US-9605296-B2 | Fluorogenic peptidase substrate | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2017-03-28 | — | — | US | disclosed |
| US-20140234887-A1 | FLUOROGENIC PEPTIDASE SUBSTRATE | CENTRE NATIONAL DE LA RECHERCHE SCIENTFIQUE (FR) | 2014-08-21 | — | — | US | disclosed |
| US-20140234887-A1 | FLUOROGENIC PEPTIDASE SUBSTRATE | CENTRE NATIONAL DE LA RECHERCHE SCIENTFIQUE (FR) | 2014-08-21 | — | — | US | disclosed |
| WO-2013045854-A1 | FLUOROGENIC PEPTIDASE SUBSTRATE | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2013-04-04 | — | — | WO | disclosed |