Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 9/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | TNKS | O95271 | 7/20 | 0.58 |
| ▸ | TNKS2 | Q9H2K2 | 7/20 | 0.58 |
| ▸ | PARP1 | P09874 | 4/20 | 0.58 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1084872 | 0.85 | GUSB (0.78) | GUSBHPGDKDM4ETNKSTNKS2 | |
| SCHEMBL29740691 | 0.85 | GUSB (0.78) | GUSBHPGDKDM4ETNKSTNKS2 | |
| SCHEMBL4579539 | 0.84 | GUSB (0.67) | GUSBHPGDKDM4ETNKSTNKS2 | |
| SCHEMBL7160589 | 0.82 | GUSB (1.00) | GUSBHPGDKDM4E | |
| SCHEMBL31238756 | 0.82 | GUSB (1.00) | GUSBHPGDKDM4E | |
| SCHEMBL10205334 | 0.82 | GUSB (0.68) | GUSBHPGDKDM4ETNKSTNKS2 | |
| SCHEMBL4579536 | 0.81 | GUSB (0.63) | GUSBHPGDKDM4ETNKSTNKS2 | |
| SCHEMBL297069 | 0.81 | GUSB (0.67) | GUSBHPGDKDM4ETNKSTNKS2 | |
| SCHEMBL14845878 | 0.81 | GUSB (0.63) | GUSBHPGDKDM4ETNKSTNKS2 | |
| SCHEMBL802560 | 0.80 | GUSB (0.68) | GUSBHPGDKDM4ETNKSTNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090324495-A1 | COMPOUNDS AND METHODS FOR ENZYME-MEDIATED TUMOR IMAGING AND THERAPY | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090324495-A1 | COMPOUNDS AND METHODS FOR ENZYME-MEDIATED TUMOR IMAGING AND THERAPY | GAA, RNASE1, GUSB | GUSB 3/4885HPGD 334/4885KDM4E 1946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.