Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15180278 | 0.84 | SMN1; SMN2 (0.53) | ALDH1A1POLBNPC1RAB9ALMNA | |
| SCHEMBL16945695 | 0.82 | ALDH1A1 (0.59) | ALDH1A1POLBNPC1RAB9ALMNA | |
| SCHEMBL13933398 | 0.82 | LMNA (0.54) | ALDH1A1POLBNPC1RAB9ALMNA | |
| SCHEMBL2321117 | 0.82 | LMNA (0.56) | ALDH1A1POLBNPC1RAB9ALMNA | |
| SCHEMBL13615353 | 0.81 | MAPT (0.44) | ALDH1A1POLBNPC1RAB9ALMNA | |
| SCHEMBL234454 | 0.81 | LMNA (0.62) | ALDH1A1POLBNPC1RAB9ALMNA | |
| SCHEMBL5969412 | 0.81 | ALDH1A1 (0.53) | ALDH1A1POLBNPC1RAB9ALMNA | |
| Iodide SCHEMBL3822935 | 0.81 | CTSL (0.54) | ALDH1A1POLBNPC1RAB9ALMNA | |
| SCHEMBL18620840 | 0.79 | ALDH1A1 (0.51) | ALDH1A1POLBNPC1RAB9ALMNA | |
| SCHEMBL1763734 | 0.79 | LMNA (0.57) | ALDH1A1POLBNPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024032799-A1 | Preparation Method of Tetrodotoxin and its Analog | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2024-02-15 | — | — | WO | disclosed |
| US-20220386611-A1 | NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-08 | — | — | US | disclosed |
| WO-2021069569-A1 | NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-04-15 | — | — | WO | disclosed |
| EP-2483277-B1 | BENZOXEPIN PI3K INHIBITOR COMPOUNDS AND METHODS OF USE | HOFFMANN LA ROCHE (CH) | 2015-12-02 | — | — | EP | disclosed |
| CN-102762574-B | Benzoxapi 3K inhibitor compounds and methods of use | HOFFMAN-LA ROCHE LTD. (CH) | 2015-12-02 | — | — | CN | disclosed |
| US-9175009-B2 | Benzoxepin PI3K inhibitor compounds and methods of use | GENENTECH, INC. (US) | 2015-11-03 | — | — | US | disclosed |
| CN-104987345-A | BENZOXEPIN PI3K INHIBITOR COMPOUNDS AND METHODS OF USE | HOFFMANN LA ROCHE | 2015-10-21 | — | — | CN | disclosed |
| US-20150094347-A1 | BENZOXEPIN PI3K INHIBITOR COMPOUNDS AND METHODS OF USE | GENENTECH INC (US) | 2015-04-02 | — | — | US | disclosed |
| US-8952043-B2 | Benzoxepin PI3K inhibitor compounds and methods of use | GENETECH, INC. (US) | 2015-02-10 | — | — | US | disclosed |
| EP-2784078-A1 | Benzoxepin pi3k inhibitor compounds and methods of use | F. Hoffmann-La Roche AG (CH) | 2014-10-01 | — | — | EP | disclosed |
| WO-1996037497-A1 | LOW MOLECULAR WEIGHT BICYCLIC-UREA TYPE THROMBIN INHIBITORS | BIOCHEM PHARMA INC. (CA) | 1996-11-28 | — | — | WO | disclosed |
| CN-1134696-A | Substituted 5-membered heterocycles, process for their preparation and their use | CASSELLA FARBWERKE MAINKUR AG (DE) | 1996-10-30 | — | — | CN | disclosed |
| CN-1127509-A | Novel peptide derivatives | ASTRA AB (SE) | 1996-07-24 | — | — | CN | disclosed |
| EP-0701568-A1 | NEW PEPTIDE DERIVATIVES | Astra Aktiebolag (SE) | 1996-03-20 | — | — | EP | disclosed |
| EP-0701550-A1 | PROCESS FOR THE PRODUCTION OF AMINOALKYLGUANIDINES | Astra Aktiebolag (SE) | 1996-03-20 | — | — | EP | disclosed |
| US-5498724-A | Pyrazoleamidine compounds | AKTIEBOLAGET ASTRA (SE) | 1996-03-12 | — | — | US | disclosed |
| CN-1099759-A | Piperazine derivatives | MERCK PATENT GMBH (DE) | 1995-03-08 | — | — | CN | disclosed |
| WO-1994029336-A1 | NEW PEPTIDE DERIVATIVES | ASTRA AKTIEBOLAG (SE) | 1994-12-22 | — | — | WO | disclosed |
| WO-1994029269-A1 | PROCESS FOR THE PRODUCTION OF AMINOALKYLGUANIDINES | ASTRA AKTIEBOLAG (SE) | 1994-12-22 | — | — | WO | disclosed |
| US-4346078-A | Novel anticoagulant agmatine derivatives and process for the preparation thereof | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1982-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150094347-A1 | BENZOXEPIN PI3K INHIBITOR COMPOUNDS AND METHODS OF USE | BMX, NR2E1, NR2E3 | ALDH1A1 4809/4885POLB 3392/4885NPC1 894/4885 |
| US-20220386611-A1 | NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES | GLRX3, CYP4X1, CYP4F3 | ALDH1A1 4092/4885POLB 4683/4885NPC1 4034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.