Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 9/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | SLC43A1 | O75387 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14769895 | 0.86 | GAA (0.43) | GAAKMT2ANPSR1ABCB1HTT | |
| SCHEMBL14769872 | 0.83 | KMT2A (0.40) | GAAKMT2ANPSR1ABCB1HTT | |
| SCHEMBL19326490 | 0.83 | LGALS9 (0.43) | GAAKMT2ANPSR1ABCB1HTT | |
| SCHEMBL10081975 | 0.83 | LGALS9 (0.43) | GAAKMT2ANPSR1ABCB1HTT | |
| SCHEMBL475965 | 0.83 | LGALS9 (0.43) | GAAKMT2ANPSR1ABCB1HTT | |
| SCHEMBL13151599 | 0.81 | ALDH1A1 (0.47) | GAAKMT2ANPSR1HTTMAPT | |
| SCHEMBL15117573 | 0.81 | ALDH1A1 (0.47) | GAAKMT2ANPSR1HTTMAPT | |
| SCHEMBL14473769 | 0.81 | ALDH1A1 (0.47) | GAAKMT2ANPSR1HTTMAPT | |
| SCHEMBL475953 | 0.81 | ALDH1A1 (0.47) | GAAKMT2ANPSR1HTTMAPT | |
| SCHEMBL12481647 | 0.81 | ALDH1A1 (0.47) | GAAKMT2ANPSR1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2578578-A1 | METHOD FOR PRODUCING (2R)-2-FLUORO-2-C-METHYL-D-RIBONO- -LACTONE PRECURSOR | Central Glass Company, Limited (JP) | 2013-04-10 | — | — | EP | disclosed |