Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 7/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 12/20 | 0.44 |
| ▸ | AR | P10275 | 3/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16309152 | 0.85 | KDM4E (0.50) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL1314602 | 0.84 | NR3C1 (0.54) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL12236696 | 0.83 | PGR (0.49) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL2393555 | 0.83 | PGR (0.50) | PGRNR3C1ARNR3C2 | |
| SCHEMBL1316228 | 0.83 | IL6 (0.52) | PGRNR3C1ARNR3C2 | |
| SCHEMBL15133762 | 0.82 | KDM4E (0.46) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL2392249 | 0.82 | NR3C1 (0.53) | PGRNR3C1ARNR3C2 | |
| SCHEMBL12236688 | 0.81 | NR3C1 (0.46) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL2393551 | 0.81 | PGR (0.42) | PGRNR3C1ARNR3C2 | |
| SCHEMBL12236673 | 0.80 | KDM4E (0.52) | MAPTALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2085387-B1 | NOVEL 1,2-DIHYDROQUINOLINE DERIVATIVE HAVING SUBSTITUTED PHENYLCHALCOGENO LOWER ALKYL GROUP AND ESTER-INTRODUCED PHENYL GROUP AS SUBSTITUENTS | SANTEN PHARMACEUTICAL CO LTD (JP) | 2013-04-10 | — | — | EP | disclosed |