SCHEMBL14848419

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18355101	0.82	THRB (0.40)	THRBCA1CA2POLBAPEX1
	SCHEMBL9610496	0.81	THRB (0.33)	THRBCA1CA2POLBAPEX1
	SCHEMBL9610489	0.81	ELANE (0.40)	ELANEKDM4EPKMKIF11P2RX4
	SCHEMBL11854481	0.76	ELANE (0.36)	ELANEKDM4EPKMKIF11ALDH1A1
	Toluene SCHEMBL28087905	0.74	THRB (0.52)	THRBCA1CA2POLBAPEX1
	SCHEMBL9610503	0.71	ELANE (0.37)	ELANEKDM4EPKMKIF11P2RX4
	P-Xylene SCHEMBL11360520	0.71	THRB (0.57)	THRBCA1CA2POLBAPEX1
	Benzene SCHEMBL28145673	0.71	THRB (0.65)	THRBCA1CA2POLBAPEX1
	SCHEMBL21237064	0.71	TSHR (0.47)	THRBCA1CA2POLBAPEX1
	SCHEMBL22703675	0.70	TDP1 (0.41)	THRBCA1CA2POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.