SCHEMBL14848579

SCHEMBL14848579

c1ccc(-n2c3ccccc3c3cc(N(c4ccc5ccccc5c4)c4ccc5ccc6c(N(c7ccc8ccccc8c7)c7ccc8c(c7)c7ccccc7n8-c7ccccc7)ccc7ccc4c5c76)ccc32)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.43
▸ ATM Q13315 1/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.43
▸ F2 P00734 1/20 0.33
▸ F10 P00742 1/20 0.33
▸ PRSS1 P07477 1/20 0.33
▸ PER2 O15055 1/20 0.33
▸ CRY1 Q16526 1/20 0.33
▸ CRY2 Q49AN0 1/20 0.33
▸ ALDH1A1 P00352 2/20 0.32
▸ TSHR P16473 2/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ POLB P06746 1/20 0.32
▸ BRCA1 P38398 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ HSD17B10 Q99714 1/20 0.32
▸ ERBB2 P04626 1/20 0.31
▸ CYP1A2 P05177 1/20 0.31
▸ FYN P06241 1/20 0.31
▸ MAOA P21397 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14848517 0.93 KDM4E (0.45) KDM4EATML3MBTL1F2F10
SCHEMBL12242941 0.90 KDM4E (0.47) KDM4EATML3MBTL1F2F10
SCHEMBL18416092 0.90 KDM4E (0.40) KDM4EATML3MBTL1ALDH1A1TSHR
SCHEMBL12372912 0.89 KDM4E (0.44) KDM4EATML3MBTL1ALDH1A1TSHR
SCHEMBL7248759 0.88 L3MBTL1 (0.35) KDM4EATML3MBTL1ALDH1A1TSHR
SCHEMBL14848602 0.87 L3MBTL1 (0.40) KDM4EATML3MBTL1ALDH1A1TSHR
SCHEMBL20349159 0.87 KDM4E (0.40) KDM4EATML3MBTL1ALDH1A1TSHR
SCHEMBL16520682 0.87 KDM4E (0.40) KDM4EATML3MBTL1F2F10
SCHEMBL10087124 0.87 KDM4E (0.53) KDM4EATML3MBTL1F2F10
SCHEMBL8928247 0.87 KDM4E (0.53) KDM4EATML3MBTL1F2F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11158812-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and pyrene-based compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2021-10-26 — — US disclosed
US-20190273207-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Pyrene-Based Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-09-05 — — US disclosed
US-10230052-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and pyrene-based compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-03-12 — — US disclosed
US-20180190905-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Pyrene-Based Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-07-05 — — US disclosed
US-20180190905-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Pyrene-Based Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-07-05 — — US disclosed
US-9911923-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and pyrene-based compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-03-06 — — US disclosed
US-20160254451-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Pyrene-Based Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-09-01 — — US disclosed
US-20160254451-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Pyrene-Based Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-09-01 — — US disclosed
US-9343681-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and pyrene-based compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-05-17 — — US disclosed
US-9343681-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and pyrene-based compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-05-17 — — US disclosed
US-20130087773-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Pyrene-Based Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-04-11 — — US disclosed
US-20130087773-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Pyrene-Based Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-04-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130087773-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Pyrene-Based Compound PPOX, PNPO, ESR1 KDM4E 1990/4885ATM 3952/4885L3MBTL1 185/4885
US-20180190905-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Pyrene-Based Compound PPOX, PNPO, ESR1 KDM4E 1990/4885ATM 3952/4885L3MBTL1 185/4885
US-20190273207-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Pyrene-Based Compound PPOX, PNPO, ESR1 KDM4E 1990/4885ATM 3952/4885L3MBTL1 185/4885
US-10230052-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and pyrene-based compound PPOX, PNPO, ESR1 KDM4E 1990/4885ATM 3952/4885L3MBTL1 185/4885
US-11158812-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and pyrene-based compound PPOX, PNPO, ESR1 KDM4E 1990/4885ATM 3952/4885L3MBTL1 185/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback