SCHEMBL7248759

SCHEMBL7248759

c1ccc(N(c2ccc3c(c2)c2cc(N(c4ccccc4)c4ccc5ccc6cccc7ccc4c5c67)ccc2n3-c2ccccc2)c2ccc3ccc4cccc5ccc2c3c45)cc1

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ ATM Q13315 1/20 0.35
▸ CYP1A2 P05177 2/20 0.35
▸ ERBB2 P04626 1/20 0.35
▸ FYN P06241 1/20 0.35
▸ MAOA P21397 1/20 0.35
▸ ACHE P22303 1/20 0.35
▸ AHR P35869 1/20 0.35
▸ JAK2 O60674 1/20 0.30
▸ JAK3 P52333 1/20 0.30
▸ ALDH1A1 P00352 2/20 0.30
▸ HPGD P15428 2/20 0.30
▸ HSD17B10 Q99714 2/20 0.30
▸ CYP3A4 P08684 1/20 0.30
▸ TSHR P16473 1/20 0.30
▸ TDP1 Q9NUW8 1/20 0.30
▸ THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7254005 0.93 HPGD (0.33) L3MBTL1KDM4EATMCYP1A2ERBB2
SCHEMBL16520708 0.93 KDM4E (0.36) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL14848517 0.93 KDM4E (0.45) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL7247856 0.90 KDM4E (0.40) L3MBTL1KDM4ECYP1A2ERBB2ALDH1A1
SCHEMBL16520682 0.90 KDM4E (0.40) L3MBTL1KDM4EATMJAK2JAK3
SCHEMBL18416092 0.90 KDM4E (0.40) L3MBTL1KDM4EATMCYP1A2ERBB2
SCHEMBL14848625 0.89 GAA (0.33) L3MBTL1KDM4EATMCYP1A2ACHE
SCHEMBL16520696 0.88 KDM4E (0.33) L3MBTL1KDM4EATMALDH1A1TSHR
SCHEMBL14848579 0.88 KDM4E (0.43) L3MBTL1KDM4EATMCYP1A2ERBB2
SCHEMBL20349159 0.87 KDM4E (0.40) L3MBTL1KDM4EATMALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020107405-A1 3,6,9-Trisubstituted carbazoles for light emitting diodes ACADEMIA SINICA (TW) 2002-08-08 — — US claimed
US-7507485-B2 Electrolytic cell; indium tin anode, hole injection layer containing phthalocyanine dye, passivation cathode; red illumination efficiency LG DISPLAY CO., LTD. (KR) 2009-03-24 — — US disclosed
US-7507485-B2 Electrolytic cell; indium tin anode, hole injection layer containing phthalocyanine dye, passivation cathode; red illumination efficiency LG DISPLAY CO., LTD. (KR) 2009-03-24 — — US disclosed
US-6649772-B2 Such as 9-phenyl-3,6-bis(5(carbazol-3-yl)-thiophen-2-yl)-9H-carbazole; electroluminescence; high glass transition temperature ACADEMIA SINICA (TW) 2003-11-18 — — US disclosed
US-20020107405-A1 3,6,9-Trisubstituted carbazoles for light emitting diodes ACADEMIA SINICA (TW) 2002-08-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107405-A1 3,6,9-Trisubstituted carbazoles for light emitting diodes CBR3, CRY2, NR2E3 L3MBTL1 2095/4885KDM4E 3907/4885ATM 4645/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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