SCHEMBL14848627

SCHEMBL14848627

c1ccc(N(c2cccc(-c3ccc4c(c3)c3ccccc3n4-c3ccccc3)c2)c2ccc3ccc4c(N(c5ccccc5)c5cccc(-c6ccc7c(c6)c6ccccc6n7-c6ccccc6)c5)ccc5ccc2c3c54)cc1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 2/20 0.40
▸ KDM4E B2RXH2 1/20 0.40
▸ ATM Q13315 1/20 0.40
▸ TSPO P30536 2/20 0.35
▸ PTGER4 P35408 1/20 0.34
▸ NPY5R Q15761 1/20 0.32
▸ KMT2A Q03164 3/20 0.31
▸ IL1R1 P14778 1/20 0.31
▸ PTGES O14684 1/20 0.31
▸ MEN1 O00255 2/20 0.30
▸ ALDH1A1 P00352 2/20 0.30
▸ MAPT P10636 1/20 0.30
▸ HTT P42858 1/20 0.30
▸ RXFP1 Q9HBX9 1/20 0.30
▸ POLB P06746 1/20 0.30
▸ TSHR P16473 1/20 0.30
▸ BRCA1 P38398 1/20 0.30
▸ HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20349159 0.93 KDM4E (0.40) L3MBTL1KDM4EATMTSPOPTGER4
SCHEMBL14848602 0.93 L3MBTL1 (0.40) L3MBTL1KDM4EATMTSPOKMT2A
SCHEMBL14848553 0.93 KDM4E (0.42) L3MBTL1KDM4EATMTSPOPTGER4
SCHEMBL14848701 0.93 KDM4E (0.38) L3MBTL1KDM4EATMTSPOPTGER4
SCHEMBL14848517 0.90 KDM4E (0.45) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL16520684 0.87 KDM4E (0.33) L3MBTL1KDM4EATMALDH1A1TSHR
SCHEMBL17194674 0.87 L3MBTL1 (0.43) L3MBTL1KDM4EATMTSPOPTGER4
SCHEMBL14755983 0.87 KDM4E (0.38) L3MBTL1KDM4EATMTSPOPTGER4
SCHEMBL14848556 0.87 KDM4E (0.38) L3MBTL1KDM4EATMTSPOPTGER4
SCHEMBL20435180 0.86 KDM4E (0.38) L3MBTL1KDM4EATMTSPOPTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11158812-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and pyrene-based compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2021-10-26 — — US disclosed
US-20190273207-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Pyrene-Based Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-09-05 — — US disclosed
US-10230052-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and pyrene-based compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-03-12 — — US disclosed
US-20180190905-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Pyrene-Based Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-07-05 — — US disclosed
US-20180190905-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Pyrene-Based Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-07-05 — — US disclosed
US-9911923-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and pyrene-based compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-03-06 — — US disclosed
US-9911923-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and pyrene-based compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-03-06 — — US disclosed
US-20160254451-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Pyrene-Based Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-09-01 — — US disclosed
US-20160254451-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Pyrene-Based Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-09-01 — — US disclosed
US-9343681-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and pyrene-based compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-05-17 — — US disclosed
US-9343681-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and pyrene-based compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-05-17 — — US disclosed
US-20130087773-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Pyrene-Based Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-04-11 — — US disclosed
US-20130087773-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Pyrene-Based Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-04-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130087773-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Pyrene-Based Compound PPOX, PNPO, ESR1 L3MBTL1 185/4885KDM4E 1990/4885ATM 3952/4885
US-20180190905-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Pyrene-Based Compound PPOX, PNPO, ESR1 L3MBTL1 185/4885KDM4E 1990/4885ATM 3952/4885
US-20190273207-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Pyrene-Based Compound PPOX, PNPO, ESR1 L3MBTL1 185/4885KDM4E 1990/4885ATM 3952/4885
US-10230052-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and pyrene-based compound PPOX, PNPO, ESR1 L3MBTL1 185/4885KDM4E 1990/4885ATM 3952/4885
US-11158812-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and pyrene-based compound PPOX, PNPO, ESR1 L3MBTL1 185/4885KDM4E 1990/4885ATM 3952/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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