SCHEMBL14848701

SCHEMBL14848701

c1ccc(-n2c3ccccc3c3cc(-c4cccc(N(c5cccc6ccccc56)c5ccc6ccc7c(N(c8cccc(-c9ccc%10c(c9)c9ccccc9n%10-c9ccccc9)c8)c8cccc9ccccc89)ccc8ccc5c6c87)c4)ccc32)cc1

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.38
▸ ATM Q13315 1/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.38
▸ TSPO P30536 1/20 0.32
▸ SIGMAR1 Q99720 2/20 0.32
▸ PTGER4 P35408 1/20 0.31
▸ PTGES O14684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14848627 0.93 L3MBTL1 (0.40) KDM4EATML3MBTL1TSPOPTGER4
SCHEMBL17194674 0.89 L3MBTL1 (0.43) KDM4EATML3MBTL1TSPOSIGMAR1
SCHEMBL14848602 0.88 L3MBTL1 (0.40) KDM4EATML3MBTL1TSPO
SCHEMBL17056417 0.88 L3MBTL1 (0.44) KDM4EATML3MBTL1SIGMAR1
SCHEMBL19151943 0.87 L3MBTL1 (0.41) KDM4EATML3MBTL1TSPOSIGMAR1
SCHEMBL13803330 0.87 L3MBTL1 (0.41) KDM4EATML3MBTL1TSPOSIGMAR1
SCHEMBL26593170 0.87 KDM4E (0.35) KDM4EATML3MBTL1TSPO
SCHEMBL16947149 0.87 L3MBTL1 (0.43) KDM4EATML3MBTL1TSPOSIGMAR1
SCHEMBL16985948 0.86 KDM4E (0.35) KDM4EATML3MBTL1TSPOPTGER4
SCHEMBL20349159 0.86 KDM4E (0.40) KDM4EATML3MBTL1TSPOPTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11158812-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and pyrene-based compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2021-10-26 — — US disclosed
US-20190273207-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Pyrene-Based Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-09-05 — — US disclosed
US-10230052-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and pyrene-based compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-03-12 — — US disclosed
US-20180190905-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Pyrene-Based Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-07-05 — — US disclosed
US-20180190905-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Pyrene-Based Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-07-05 — — US disclosed
US-9911923-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and pyrene-based compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-03-06 — — US disclosed
US-9911923-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and pyrene-based compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-03-06 — — US disclosed
US-20160254451-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Pyrene-Based Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-09-01 — — US disclosed
US-20160254451-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Pyrene-Based Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-09-01 — — US disclosed
US-9343681-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and pyrene-based compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-05-17 — — US disclosed
US-9343681-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and pyrene-based compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-05-17 — — US disclosed
US-20130087773-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Pyrene-Based Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-04-11 — — US disclosed
US-20130087773-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Pyrene-Based Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-04-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130087773-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Pyrene-Based Compound PPOX, PNPO, ESR1 KDM4E 1990/4885ATM 3952/4885L3MBTL1 185/4885
US-20180190905-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Pyrene-Based Compound PPOX, PNPO, ESR1 KDM4E 1990/4885ATM 3952/4885L3MBTL1 185/4885
US-20190273207-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Pyrene-Based Compound PPOX, PNPO, ESR1 KDM4E 1990/4885ATM 3952/4885L3MBTL1 185/4885
US-10230052-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and pyrene-based compound PPOX, PNPO, ESR1 KDM4E 1990/4885ATM 3952/4885L3MBTL1 185/4885
US-11158812-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and pyrene-based compound PPOX, PNPO, ESR1 KDM4E 1990/4885ATM 3952/4885L3MBTL1 185/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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