Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 5/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19988556 | 0.89 | HDAC8 (0.52) | HDAC8HDAC6HPGDALDH1A1HDAC2 | |
| SCHEMBL16350551 | 0.89 | HDAC8 (0.52) | HDAC8HDAC6HPGDALDH1A1HDAC2 | |
| SCHEMBL10041772 | 0.85 | CA5A (0.52) | HPGDALDH1A1CA5ATSHRHTT | |
| SCHEMBL4623865 | 0.85 | CA5A (0.52) | HPGDALDH1A1CA5ATSHRHTT | |
| SCHEMBL4478521 | 0.80 | HDAC8 (0.60) | HDAC8HDAC6HPGDALDH1A1HDAC2 | |
| SCHEMBL14067800 | 0.78 | KMT2A (0.48) | ALDH1A1CA5ALMNAPRKCI | |
| SCHEMBL20404600 | 0.77 | HDAC8 (0.42) | HDAC8HDAC6HPGDALDH1A1HDAC2 | |
| Acetone SCHEMBL28498158 | 0.75 | LMNA (0.38) | HDAC8HPGDALDH1A1CA5ATSHR | |
| SCHEMBL15545731 | 0.74 | HDAC8 (0.64) | HDAC8HDAC6HPGDALDH1A1HDAC2 | |
| SCHEMBL3786661 | 0.74 | HDAC8 (0.50) | HDAC8HDAC6HPGDALDH1A1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130089727-A1 | Thin film composites | NILSEN, TOM NILS (NO) | 2013-04-11 | — | — | US | disclosed |