Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 4/20 | 0.39 |
| ▸ | TERT | O14746 | 3/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | PPARD | Q03181 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | F7 | P08709 | 2/20 | 0.39 |
| ▸ | F3 | P13726 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19128348 | 1.00 | TDP1 (0.43) | TDP1PPARGMAPTCYP19A1FFAR1 | |
| SCHEMBL19128346 | 1.00 | TDP1 (0.43) | TDP1PPARGMAPTCYP19A1FFAR1 | |
| SCHEMBL4708110 | 0.85 | ALDH1A1 (0.56) | TDP1PPARGMAPTCYP19A1FFAR1 | |
| SCHEMBL15241269 | 0.85 | ALDH1A1 (0.56) | TDP1PPARGMAPTCYP19A1FFAR1 | |
| SCHEMBL4708111 | 0.85 | ALDH1A1 (0.56) | TDP1PPARGMAPTCYP19A1FFAR1 | |
| SCHEMBL16980399 | 0.84 | FAAH (0.59) | TDP1PPARGMAPTCYP19A1FFAR1 | |
| SCHEMBL9389884 | 0.83 | TDP1 (0.41) | TDP1PPARGMAPTCYP19A1FFAR1 | |
| SCHEMBL726217 | 0.83 | TDP1 (0.41) | TDP1PPARGMAPTCYP19A1FFAR1 | |
| SCHEMBL9389879 | 0.83 | TDP1 (0.41) | TDP1PPARGMAPTCYP19A1FFAR1 | |
| SCHEMBL726218 | 0.83 | TDP1 (0.41) | TDP1PPARGMAPTCYP19A1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8865122-B2 | Methods and compositions for protein labelling | GENENTECH, INC. (US) | 2014-10-21 | — | — | US | disclosed |
| US-20130089884-A1 | Protein Modification from the Oxidation of Clickable Polyunsaturated Fatty Acid Analogs | Life Technologies Corporation (US) | 2013-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130089884-A1 | Protein Modification from the Oxidation of Clickable Polyunsaturated Fatty Acid Analogs | FASN, ACSL6, FADS1 | TDP1 4209/4885PPARG 200/4885MAPT 4637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.