Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30298056 | 0.79 | HDAC2 (0.49) | HDAC2RAB9AHDAC3HDAC1HDAC4 | |
| SCHEMBL268855 | 0.76 | RAB9A (0.73) | RAB9AHDAC1NPC1MAPTLMNA | |
| SCHEMBL450084 | 0.76 | RAB9A (0.85) | HDAC2RAB9AHDAC3HDAC1NPC1 | |
| SCHEMBL5163196 | 0.76 | HDAC3 (0.51) | HDAC2RAB9AHDAC3HDAC1HDAC4 | |
| SCHEMBL9585720 | 0.75 | BCL2L1 (0.66) | HDAC2RAB9AHDAC3HDAC1HDAC4 | |
| SCHEMBL5162744 | 0.75 | HDAC3 (0.57) | HDAC2RAB9AHDAC3HDAC1HDAC4 | |
| SCHEMBL5160499 | 0.75 | HDAC3 (0.57) | HDAC2RAB9AHDAC3HDAC1HDAC4 | |
| SCHEMBL5162433 | 0.74 | HDAC3 (0.60) | HDAC2RAB9AHDAC3HDAC1HDAC4 | |
| SCHEMBL15979634 | 0.74 | BCL2L1 (0.51) | HDAC2RAB9AHDAC3HDAC1NPC1 | |
| SCHEMBL14849577 | 0.74 | RAB9A (0.56) | RAB9AHDAC1NPC1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130090460-A1 | RARE EARTH METAL COMPLEX | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2013-04-11 | — | — | US | disclosed |
| US-20130090460-A1 | RARE EARTH METAL COMPLEX | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2013-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130090460-A1 | RARE EARTH METAL COMPLEX | AP1M1, KCNMA1, DDRGK1 | HDAC2 690/4885RAB9A 3349/4885HDAC3 1112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.