Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 3/20 | 0.48 |
| ▸ | MTOR | P42345 | 2/20 | 0.48 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 2/20 | 0.40 |
| ▸ | FYN | P06241 | 4/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.36 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.36 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14852518 | 0.83 | DYRK1A (0.56) | PIK3CAMTORMAP3K14KCNH2FLT3 | |
| SCHEMBL26178953 | 0.80 | KDR (0.53) | PIK3CAMTORMAP3K14KCNH2FLT3 | |
| SCHEMBL15756786 | 0.80 | FLT3 (0.59) | PIK3CAMTORMAP3K14FLT3FYN | |
| SCHEMBL15288131 | 0.80 | FYN (0.55) | PIK3CAMTORMAP3K14KCNH2FLT3 | |
| SCHEMBL15756965 | 0.79 | MAP3K14 (0.54) | PIK3CAMTORMAP3K14KCNH2FLT3 | |
| SCHEMBL4253251 | 0.79 | CHEK1 (0.50) | PIK3CAMTORKCNH2FYNMKNK1 | |
| SCHEMBL20146927 | 0.78 | MKNK1 (0.57) | PIK3CAMTORKCNH2FLT3FYN | |
| SCHEMBL3847512 | 0.78 | MKNK1 (0.51) | PIK3CAMTORMAP3K14FYNMKNK1 | |
| SCHEMBL4254179 | 0.78 | MAP3K14 (0.56) | PIK3CAMTORMAP3K14FLT3FYN | |
| SCHEMBL3846712 | 0.77 | MKNK1 (0.61) | PIK3CAMTORMAP3K14FYNMKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013051672-A1 | MEDICINAL AGENT COMPRISING THIAZOLIDINE DERIVATIVE OR SALT THEREOF AS ACTIVE INGREDIENT | 株式会社ヤクルト本社 (JP) | 2013-04-11 | — | — | WO | disclosed |