Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 6/20 | 0.59 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.59 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.59 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.59 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.59 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.59 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.59 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.59 |
| ▸ | SRC | P12931 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.58 |
| ▸ | P2RY11 | Q96G91 | 2/20 | 0.58 |
| ▸ | TRPM2 | O94759 | 2/20 | 0.58 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.58 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.58 |
| ▸ | LDHA | P00338 | 1/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.58 |
| ▸ | FBP1 | P09467 | 1/20 | 0.58 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14831998 | 0.88 | DNPH1 (0.73) | P2RY1P2RX3P2RY2P2RX1P2RX4 | |
| SCHEMBL3862068 | 0.88 | P2RX3 (0.61) | P2RY1ENPP1P2RX3P2RY2P2RX1 | |
| SCHEMBL29015761 | 0.88 | P2RY1 (0.77) | P2RY1ENPP1P2RX3P2RY2P2RX1 | |
| SCHEMBL15084467 | 0.86 | ADORA1 (0.67) | P2RY1P2RY12P2RX3P2RY2P2RX1 | |
| SCHEMBL3858337 | 0.84 | P2RY1 (0.62) | P2RY1ENPP1P2RX3P2RY2P2RX1 | |
| SCHEMBL3792441 | 0.82 | P2RY1 (0.82) | P2RY1ENPP1P2RX3P2RY2P2RX1 | |
| SCHEMBL28755762 | 0.82 | P2RY1 (0.82) | P2RY1ENPP1P2RX3P2RY2P2RX1 | |
| SCHEMBL5838786 | 0.82 | P2RY1 (0.82) | P2RY1ENPP1P2RX3P2RY2P2RX1 | |
| SCHEMBL15038133 | 0.82 | P2RY1 (0.65) | P2RY1P2RX3P2RY2P2RX1P2RX4 | |
| SCHEMBL15108925 | 0.82 | P2RY1 (0.81) | P2RY1ENPP1P2RX3P2RY2P2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013052523-A1 | MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF | modeRNA Therapeutics (US) | 2013-04-11 | — | — | WO | disclosed |