Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 3/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.40 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Acetate SCHEMBL29038293 | 1.00 | ALDH1A1 (0.52) | ALDH1A1LMNAHSD17B10ZDHHC7FAAH | |
| Ethyl Acetate SCHEMBL278533 | 1.00 | ALDH1A1 (0.52) | ALDH1A1LMNAHSD17B10ZDHHC7FAAH | |
| Ethyl Acetate SCHEMBL1268307 | 1.00 | ALDH1A1 (0.52) | ALDH1A1LMNAHSD17B10ZDHHC7FAAH | |
| Ethyl Acetate SCHEMBL8532167 | 0.98 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10ZDHHC7FAAH | |
| Ethyl Acetate SCHEMBL28478460 | 0.98 | ALDH1A1 (0.54) | ALDH1A1LMNAHSD17B10ZDHHC7FAAH | |
| Heptane SCHEMBL4621147 | 0.88 | ALDH1A1 (0.61) | ALDH1A1LMNAHSD17B10ZDHHC7FAAH | |
| Heptane SCHEMBL17105901 | 0.87 | ALDH1A1 (0.54) | ALDH1A1LMNAHSD17B10FAAHMAPT | |
| Heptane SCHEMBL4126646 | 0.86 | ALDH1A1 (0.58) | ALDH1A1LMNAHSD17B10ZDHHC7FAAH | |
| Hexane SCHEMBL8542408 | 0.86 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10ZDHHC7FAAH | |
| Hexane SCHEMBL133237 | 0.86 | ALDH1A1 (0.64) | ALDH1A1LMNAHSD17B10ZDHHC7FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11851425-B2 | Combination treatments comprising administration of 1H-pyrazolo[4,3-B]pyridines | H. LUNDBECK A/S (DK) | 2023-12-26 | — | — | US | disclosed |
| CN-111556871-B | 1H-pyrazolo [4,3-b ] pyridines as PDE1 inhibitors | H.隆德贝克有限公司 | 2023-07-07 | — | — | CN | disclosed |
| CN-111491936-B | Macrocyclic compounds as PDE1 inhibitors | H.隆德贝克有限公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-110903242-B | Preparation method of Luo Shasi his intermediate | 四川科伦药物研究院有限公司 | 2023-05-12 | — | — | CN | disclosed |
| US-11634416-B2 | Combination treatments comprising administration of 1H-pyrazolo[4,3-b]pyridines | H. LUNDBECK A/S (DK) | 2023-04-25 | — | — | US | disclosed |
| CN-111465410-B | Combination therapy comprising administration of 1H-pyrazolo [4,3-B ] pyridine | H.隆德贝克有限公司 | 2022-10-25 | — | — | CN | disclosed |
| CN-111526890-B | Combination therapy comprising administration of 1H-pyrazolo [4,3-B ] pyridine | H.隆德贝克有限公司 | 2022-10-14 | — | — | CN | disclosed |
| US-11389464-B2 | Arginase inhibitors as therapeutics | MARS, INCORPORATED (US) | 2022-07-19 | — | — | US | disclosed |
| EP-3723807-B1 | COMBINATION TREATMENTS COMPRISING ADMINISTRATION OF 1H-PYRAZOLO[4,3-B]PYRIDINES | H LUNDBECK AS (DK) | 2021-10-20 | — | — | EP | disclosed |
| EP-3723808-B1 | COMBINATION TREATMENTS COMPRISING ADMINISTRATION OF 1H-PYRAZOLO[4,3-B]PYRIDINES | H LUNDBECK AS (DK) | 2021-10-20 | — | — | EP | disclosed |
| EP-1217434-A2 | Silver halide photographic element | EASTMAN KODAK COMPANY (US) | 2002-06-26 | — | — | EP | disclosed |
| US-6329130-B1 | EMULSION LAYER WITH YELLOW DYE FORMING COUPLER AROMATIC AMIDE AMINE ESTER WITH ETHER | EASTMAN KODAK COMPANY | 2001-12-11 | — | — | US | disclosed |
| US-6262095-B1 | TREATMENT OF ILLNESS ASSOCIATED WITH AN ALTERATION IN VENOUS FUNCTION AND/OR INFLAMMATORY EDEMA | LABORATOIRE INNOTHERA (FR) | 2001-07-17 | — | — | US | disclosed |
| US-5981544-A | Mono-- or diketone tetracyclic derivatives and therapeutical uses thereof | LABORATOIRE INNOTHERA (FR) | 1999-11-09 | — | — | US | disclosed |
| CN-1214691-A | Process for preparation of N-methyl-D-phenylalanyl-N-[1-[3-[(aminoiminomethyl)-amino] propyl]-3,3-difluoro-2-oxohexyl]-L-prolinamide | HOECHST MARION ROUSSEL INC (US) | 1999-04-21 | — | — | CN | disclosed |
| EP-0560424-B1 | Carbamic acid solubilized smearing couplers | EASTMAN KODAK CO (US) | 1996-07-03 | — | — | EP | disclosed |
| US-5246820-A | Precursor which hydrolyzes than decomposes to carbon dioxide and non-diffusable amine | EASTMAN KODAK COMPANY | 1993-09-21 | — | — | US | disclosed |
| EP-0560424-A1 | Carbamic acid solubilized smearing couplers | EASTMAN KODAK COMPANY (US) | 1993-09-15 | — | — | EP | disclosed |
| EP-0540729-A1 | BLOCKED FILTER DYES FOR PHOTOGRAPHIC MATERIAL AND PROCESS | EASTMAN KODAK COMPANY (US) | 1993-05-12 | — | — | EP | disclosed |
| WO-1992021064-A1 | BLOCKED FILTER DYES FOR PHOTOGRAPHIC MATERIAL AND PROCESS | EASTMAN KODAK COMPANY (US) | 1992-11-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11389464-B2 | Arginase inhibitors as therapeutics | ARG1, ARG2, PRMT1 | ALDH1A1 1448/4885LMNA 3140/4885HSD17B10 2786/4885 |
| US-11851425-B2 | Combination treatments comprising administration of 1H-pyrazolo[4,3-B]pyridines | PDE3B, PDE1B, PDE12 | ALDH1A1 280/4885LMNA 2745/4885HSD17B10 1194/4885 |
| US-11634416-B2 | Combination treatments comprising administration of 1H-pyrazolo[4,3-b]pyridines | PDE1B, PDE3B, PDE1A | ALDH1A1 210/4885LMNA 3970/4885HSD17B10 688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.