Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DDO | Q99489 | 1/20 | 0.32 |
| ▸ | DGAT2 | Q96PD7 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10070601 | 0.83 | SPHK1 (0.37) | HTR2ASLC6A5LMNACYP1A2CYP3A4 | |
| SCHEMBL185855 | 0.82 | KDM4E (0.41) | LMNAALDH1A1BDKRB1KDM4EMEN1 | |
| SCHEMBL200210 | 0.80 | HTR2A (0.33) | HTR2ASLC6A5LMNACYP1A2CYP3A4 | |
| SCHEMBL186114 | 0.73 | KDM4E (0.43) | LMNACYP1A2ALDH1A1BDKRB1KDM4E | |
| SCHEMBL11984274 | 0.72 | BDKRB1 (0.39) | LMNAALDH1A1BDKRB1KDM4EMEN1 | |
| SCHEMBL185854 | 0.70 | KDM4E (0.45) | LMNAL3MBTL1TSHRALDH1A1BDKRB1 | |
| SCHEMBL2805627 | 0.70 | KDM4E (0.45) | LMNAL3MBTL1TSHRALDH1A1BDKRB1 | |
| SCHEMBL14856657 | 0.70 | KDM4E (0.45) | L3MBTL1ALDH1A1KDM4EDGAT2SMN1; SMN2 | |
| SCHEMBL185596 | 0.67 | VNN1 (0.38) | BDKRB1DGAT2 | |
| SCHEMBL2787463 | 0.67 | VNN1 (0.38) | BDKRB1DGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401256-B1 | Compounds as bradykinin B1 antagonists | BOEHRINGER INGELHEIM INT (DE) | 2013-04-17 | — | — | EP | disclosed |