SCHEMBL1485876

SCHEMBL1485876

Nc1cc2c(OCCCS(=O)(=O)O)cc(S(=O)(=O)O)cc2cc1S(=O)(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CASP6 P55212 3/20 0.40
▸ ALDH1A1 P00352 1/20 0.40
▸ CYP2C9 P11712 1/20 0.40
▸ CYP2C19 P33261 1/20 0.40
▸ HSD17B10 Q99714 1/20 0.40
▸ NT5E P21589 2/20 0.35
▸ NSD2 O96028 2/20 0.35
▸ DUSP3 P51452 1/20 0.35
▸ PTPN5 P54829 1/20 0.35
▸ PTPN11 Q06124 1/20 0.35
▸ CYP1A2 P05177 2/20 0.34
▸ ENPP2 Q13822 1/20 0.32
▸ SUMO2 P61956 2/20 0.32
▸ SUMO1 P63165 2/20 0.32
▸ SENP7 Q9BQF6 2/20 0.32
▸ SENP2 Q9HC62 2/20 0.32
▸ GAA P10253 1/20 0.31
▸ PLCG1 P19174 1/20 0.31
▸ DNMT1 P26358 1/20 0.31
▸ L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29682784 1.00 CASP6 (0.40) CASP6ALDH1A1CYP2C9CYP2C19HSD17B10
SCHEMBL20597181 0.96 CASP6 (0.39) CASP6ALDH1A1CYP2C9CYP2C19HSD17B10
SCHEMBL29683090 0.84 NT5E (0.55) CASP6ALDH1A1CYP2C9CYP2C19HSD17B10
SCHEMBL1485869 0.84 NT5E (0.55) CASP6ALDH1A1CYP2C9CYP2C19HSD17B10
SCHEMBL29682799 0.81 CASP6 (0.55) CASP6ALDH1A1CYP2C9CYP2C19HSD17B10
SCHEMBL1485804 0.81 CASP6 (0.55) CASP6ALDH1A1CYP2C9CYP2C19HSD17B10
SCHEMBL29682858 0.80 NT5E (0.53) CASP6ALDH1A1CYP2C9CYP2C19HSD17B10
SCHEMBL1485941 0.80 NT5E (0.53) CASP6ALDH1A1CYP2C9CYP2C19HSD17B10
SCHEMBL23706460 0.79 HTR1B (0.38) CASP6ALDH1A1CYP2C9CYP2C19HSD17B10
SCHEMBL29740728 0.79 HTR1B (0.38) CASP6ALDH1A1CYP2C9CYP2C19HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114945636-B Azo compound or salt thereof, polarizing film, polarizing plate, and display device 日本化药株式会社 2024-07-12 — — CN disclosed
CN-114008143-B Azo compound, polarizing film containing the same, and polarizing plate 日本化药株式会社 2024-05-14 — — CN disclosed
CN-116261924-A Polarizing element, polarizing plate, and display device provided with same 日本化药株式会社 2023-06-13 — — CN disclosed
CN-114945636-A Azo compound or salt thereof, and dye-based polarizing film, dye-based polarizing plate, and display device containing the same 日本化药株式会社 2022-08-26 — — CN disclosed
CN-111433290-B Azo compound or salt thereof, and polarizing element, polarizing plate and display device each comprising the same 日本化药株式会社 2022-06-14 — — CN disclosed
CN-114008143-A Azo compound, polarizing film containing the same, and polarizing plate 日本化药株式会社 2022-02-01 — — CN disclosed
CN-113795554-A Achromatic polarizing element, and achromatic polarizing plate and display device using same 日本化药株式会社 2021-12-14 — — CN disclosed
WO-2021153374-A1 AZO COMPOUND OR SALT THEREOF, AND DYE-BASED POLARIZING FILM, DYE-BASED POLARIZING PLATE AND DISPLAY DEVICE EACH CONTAINING SAME 日本化薬株式会社 2021-08-05 — — WO disclosed
CN-108699346-B Azo compound or salt thereof, and polarizing film containing azo compound or salt thereof 日本化药株式会社 2021-06-29 — — CN disclosed
CN-110249008-B Azo compound or salt thereof, and dye-based polarizing film, dye-based polarizing plate, and liquid crystal display device each containing the same 日本化药株式会社 2021-06-11 — — CN disclosed
US-20160103362-A1 Azo Compound and Salt Thereof, And Dye-Based Polarizing Film And Polarizing Plate Containing The Same POLATECHNO CO LTD (JP) 2016-04-14 — — US disclosed
US-9244194-B2 Azo compound and salt thereof, and dye-based polarizing film and polarizing plate containing the same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2016-01-26 — — US disclosed
US-20150337134-A1 Azo Compound And Salt Thereof, And Dye-Based Polarizing Film And Polarizing Plate Containing The Same NIPPON KAYAKU KK (JP) 2015-11-26 — — US disclosed
US-20140218797-A1 Polarizing Element And Polarizing Plate POLATECHNO CO., LTD. (JP) 2014-08-07 — — US disclosed
EP-2752694-A1 POLARIZING ELEMENT AND POLARIZING PLATE Nippon Kayaku Kabushiki Kaisha (JP) 2014-07-09 — — EP disclosed
EP-2674460-A1 AZO COMPOUND, SALT THEREOF, AND DYE-BASED POLARIZING FILM AND POLARIZING PLATE CONTAINING SAME Nippon Kayaku Kabushiki Kaisha (JP) 2013-12-18 — — EP disclosed
US-20130314786-A1 Azo Compound And Salt Thereof, And Dye-Based Polarizing Film And Polarizing Plate Containing The Same POLATECHNO CO., LTD. (JP) 2013-11-28 — — US disclosed
US-8477268-B2 Azo compound and salts thereof, as well as dye-based polarization films and polarizing plates comprising the same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2013-07-02 — — US disclosed
US-20110164208-A1 Azo Compound And Salts Thereof, As Well As Dye-Based Polarization Films And Polarizing Plates Comprising The Same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-07-07 — — US disclosed
US-20110075076-A1 Azo Compounds, And Dye-Based Polarizing Films And Polarizing Plates Comprising The Same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-03-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160103362-A1 Azo Compound and Salt Thereof, And Dye-Based Polarizing Film And Polarizing Plate Containing The Same TYR, CRY1, NAP1L4 CASP6 3406/4885ALDH1A1 2090/4885CYP2C9 1076/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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