SCHEMBL1485941

SCHEMBL1485941

Nc1ccc2cc(S(=O)(=O)O)cc(OCCCCS(=O)(=O)O)c2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NT5E P21589 4/20 0.53
▸ CASP6 P55212 4/20 0.44
▸ NSD2 O96028 3/20 0.44
▸ DUSP3 P51452 2/20 0.44
▸ PTPN5 P54829 2/20 0.44
▸ PTPN11 Q06124 2/20 0.44
▸ ALDH1A1 P00352 5/20 0.43
▸ HSD17B10 Q99714 3/20 0.43
▸ CYP2C9 P11712 1/20 0.43
▸ CYP2C19 P33261 1/20 0.43
▸ S1PR3 Q99500 1/20 0.35
▸ TSHR P16473 2/20 0.35
▸ TDP1 Q9NUW8 1/20 0.35
▸ CYP1A2 P05177 1/20 0.34
▸ CTDSP1 Q9GZU7 1/20 0.33
▸ CYP2D6 P10635 1/20 0.33
▸ SUMO2 P61956 1/20 0.32
▸ SUMO1 P63165 1/20 0.32
▸ SENP7 Q9BQF6 1/20 0.32
▸ SENP2 Q9HC62 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29682858 1.00 NT5E (0.53) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL29683090 0.96 NT5E (0.55) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL1485869 0.96 NT5E (0.55) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL29682968 0.90 CASP6 (0.53) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL1485837 0.90 CASP6 (0.53) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL29682799 0.86 CASP6 (0.55) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL1485804 0.86 CASP6 (0.55) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL20597181 0.84 CASP6 (0.39) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL18419447 0.83 CASP6 (0.56) NT5ECASP6TDP1CTDSP1LMNA
SCHEMBL1485876 0.80 CASP6 (0.40) NT5ECASP6NSD2DUSP3PTPN5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114945636-B Azo compound or salt thereof, polarizing film, polarizing plate, and display device 日本化药株式会社 2024-07-12 — — CN disclosed
CN-114008143-B Azo compound, polarizing film containing the same, and polarizing plate 日本化药株式会社 2024-05-14 — — CN disclosed
CN-116261924-A Polarizing element, polarizing plate, and display device provided with same 日本化药株式会社 2023-06-13 — — CN disclosed
CN-114945636-A Azo compound or salt thereof, and dye-based polarizing film, dye-based polarizing plate, and display device containing the same 日本化药株式会社 2022-08-26 — — CN disclosed
CN-111433290-B Azo compound or salt thereof, and polarizing element, polarizing plate and display device each comprising the same 日本化药株式会社 2022-06-14 — — CN disclosed
CN-114008143-A Azo compound, polarizing film containing the same, and polarizing plate 日本化药株式会社 2022-02-01 — — CN disclosed
CN-113795554-A Achromatic polarizing element, and achromatic polarizing plate and display device using same 日本化药株式会社 2021-12-14 — — CN disclosed
WO-2021153374-A1 AZO COMPOUND OR SALT THEREOF, AND DYE-BASED POLARIZING FILM, DYE-BASED POLARIZING PLATE AND DISPLAY DEVICE EACH CONTAINING SAME 日本化薬株式会社 2021-08-05 — — WO disclosed
CN-108699346-B Azo compound or salt thereof, and polarizing film containing azo compound or salt thereof 日本化药株式会社 2021-06-29 — — CN disclosed
CN-110249008-B Azo compound or salt thereof, and dye-based polarizing film, dye-based polarizing plate, and liquid crystal display device each containing the same 日本化药株式会社 2021-06-11 — — CN disclosed
US-20160103362-A1 Azo Compound and Salt Thereof, And Dye-Based Polarizing Film And Polarizing Plate Containing The Same POLATECHNO CO LTD (JP) 2016-04-14 — — US disclosed
US-9244194-B2 Azo compound and salt thereof, and dye-based polarizing film and polarizing plate containing the same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2016-01-26 — — US disclosed
US-20150337134-A1 Azo Compound And Salt Thereof, And Dye-Based Polarizing Film And Polarizing Plate Containing The Same NIPPON KAYAKU KK (JP) 2015-11-26 — — US disclosed
US-20140218797-A1 Polarizing Element And Polarizing Plate POLATECHNO CO., LTD. (JP) 2014-08-07 — — US disclosed
EP-2752694-A1 POLARIZING ELEMENT AND POLARIZING PLATE Nippon Kayaku Kabushiki Kaisha (JP) 2014-07-09 — — EP disclosed
EP-2674460-A1 AZO COMPOUND, SALT THEREOF, AND DYE-BASED POLARIZING FILM AND POLARIZING PLATE CONTAINING SAME Nippon Kayaku Kabushiki Kaisha (JP) 2013-12-18 — — EP disclosed
US-20130314786-A1 Azo Compound And Salt Thereof, And Dye-Based Polarizing Film And Polarizing Plate Containing The Same POLATECHNO CO., LTD. (JP) 2013-11-28 — — US disclosed
US-8477268-B2 Azo compound and salts thereof, as well as dye-based polarization films and polarizing plates comprising the same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2013-07-02 — — US disclosed
US-20110164208-A1 Azo Compound And Salts Thereof, As Well As Dye-Based Polarization Films And Polarizing Plates Comprising The Same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-07-07 — — US disclosed
US-20110075076-A1 Azo Compounds, And Dye-Based Polarizing Films And Polarizing Plates Comprising The Same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-03-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160103362-A1 Azo Compound and Salt Thereof, And Dye-Based Polarizing Film And Polarizing Plate Containing The Same TYR, CRY1, NAP1L4 NT5E 3772/4885CASP6 3406/4885NSD2 903/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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