SCHEMBL1485885

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4562062	0.95	MAOA (0.39)	MAOAMAOBACHETNFTUBB4A
	SCHEMBL4561443	0.93	TUBB4A (0.39)	TNFTUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL4562110	0.91	MAOA (0.46)	MAOAMAOBACHETNFCYP2D6
	SCHEMBL2692512	0.91	MAOA (0.48)	MAOAMAOBACHETNFCYP2D6
	SCHEMBL4561538	0.91	MAOA (0.38)	MAOAMAOBACHETNFTUBB4A
	SCHEMBL12161367	0.91	TNF (0.43)	MAOAMAOBACHETNFTUBB4A
	SCHEMBL4562406	0.91	TNF (0.46)	MAOAMAOBACHETNFTUBB4A
	SCHEMBL5944342	0.91	TNF (0.46)	MAOAMAOBACHETNFTUBB4A
	SCHEMBL2695285	0.89	MAOA (0.49)	MAOAMAOBACHETNFCYP2D6
	SCHEMBL4561540	0.89	MAOA (0.40)	MAOAMAOBACHETNFCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.