SCHEMBL148599

SCHEMBL148599

CCCCN1CCNC1=O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.63
MEN1 O00255 3/20 0.63
FAAH O00519 1/20 0.46
NAAA Q02083 1/20 0.46
SMN1; SMN2 Q16637 3/20 0.42
RAB9A P51151 2/20 0.42
ALDH1A1 P00352 6/20 0.42
POLB P06746 3/20 0.42
KDM4E B2RXH2 3/20 0.39
MAPT P10636 2/20 0.39
CYP2C9 P11712 2/20 0.39
CYP2C19 P33261 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
NPC1 O15118 1/20 0.38
HPGD P15428 1/20 0.38
TSHR P16473 1/20 0.38
HSD17B10 Q99714 1/20 0.38
RET P07949 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3420576 0.94 KMT2A (0.56) KMT2AMEN1FAAHNAAASMN1; SMN2
SCHEMBL8671910 0.92 KMT2A (0.55) KMT2AMEN1FAAHNAAASMN1; SMN2
SCHEMBL6269938 0.92 KMT2A (0.55) KMT2AMEN1FAAHNAAASMN1; SMN2
SCHEMBL8587006 0.92 KMT2A (0.55) KMT2AMEN1FAAHNAAASMN1; SMN2
SCHEMBL10868669 0.92 KMT2A (0.55) KMT2AMEN1FAAHNAAASMN1; SMN2
SCHEMBL10745323 0.92 KMT2A (0.55) KMT2AMEN1FAAHNAAASMN1; SMN2
SCHEMBL17003978 0.92 KMT2A (0.55) KMT2AMEN1FAAHNAAASMN1; SMN2
SCHEMBL6561471 0.92 KMT2A (0.55) KMT2AMEN1FAAHNAAASMN1; SMN2
SCHEMBL6890835 0.92 KMT2A (0.55) KMT2AMEN1FAAHNAAASMN1; SMN2
SCHEMBL25752209 0.92 KMT2A (0.55) KMT2AMEN1FAAHNAAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113980749-B Liquid detergent composition 广州立白企业集团有限公司 2024-01-26 CN claimed
CN-113980749-A Liquid detergent composition 广州立白企业集团有限公司 2022-01-28 CN claimed
EP-0743956-A4 PRETARGETING METHODS AND COMPOUNDS NEORX CORP (US) 1999-03-24 EP claimed
EP-0743956-A1 PRETARGETING METHODS AND COMPOUNDS NeoRx (US) 1996-11-27 EP claimed
JP-10001426-A None JP disclosed
WO-2024044728-A1 PEGYLATED LIPID COMPOUNDS AND METHODS OF USE THEREOF RENAGADE THERAPEUTICS MANAGEMENT INC. (US) 2024-02-29 WO disclosed
CN-113980749-B Liquid detergent composition 广州立白企业集团有限公司 2024-01-26 CN disclosed
EP-3736261-B1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX INC (US) 2023-10-11 EP disclosed
US-20230203087-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2023-06-29 US disclosed
US-20230203484-A1 DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO WAVE LIFE SCIENCES LTD. (SG) 2023-06-29 US disclosed
US-20230203484-A1 DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO WAVE LIFE SCIENCES LTD. (SG) 2023-06-29 US disclosed
US-20230136702-A1 Inhibitors of Human Herpesviruses THE GOVERNORS OF THE UNIVERSTIY OF ALBERTA (CA) 2023-05-04 US disclosed
EP-1295935-B1 DETERGENT COMPOSITION ARAKAWA CHEM IND (JP) 2007-03-21 EP disclosed
US-20070043045-A1 Novel high affinity thiophene-based and furan-based kinase ligands SCHERING CORPORATION 2007-02-22 US disclosed
US-7160890-B2 Compounds specific to adenosine A3 receptor and uses thereof OSI PHARMACEUTICALS, INC. (US) 2007-01-09 US disclosed
US-7018964-B2 The cleaning composition of this invention comprises, as effective components, a compound (A) represented by the formula (1) and a nonionic surfactant (B): polyoxyethylene glycol phosphate ARAKAWA CHEMICAL INDUSTRIES, LTD. (JP) 2006-03-28 US disclosed
US-20030181349-A1 The cleaning composition of this invention comprises, as effective components, a compound (A) represented by the formula (1) and a nonionic surfactant (B): polyoxyethylene glycol phosphate ARAKAWA CHEMICAL INDUSTRIES, LTD. (JP) 2003-09-25 US disclosed
EP-1295935-A1 DETERGENT COMPOSITION Arakawa Chemical Industries, Ltd. (JP) 2003-03-26 EP disclosed
US-5753661-A TREATMENT OF NERVOUS SYSTEM, PSYCHOLOGICAL DISORDERS; ANTIDEPRESSANTS H. LUNDBECK A/S (DK) 1998-05-19 US disclosed
JP-H101426-A HAIR TREATMENT COMPOSITION KAO CORP 1998-01-06 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230136702-A1 Inhibitors of Human Herpesviruses RPL5, RPL35, HAVCR2 KMT2A 329/4885MEN1 1255/4885FAAH 3906/4885
US-20230203087-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF RNGTT, NSUN2, ALKBH1 KMT2A 742/4885MEN1 3176/4885FAAH 4105/4885
US-20070043045-A1 Novel high affinity thiophene-based and furan-based kinase ligands CDKL2, CDK2, CDKL1 KMT2A 806/4885MEN1 3348/4885FAAH 2437/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.