SCHEMBL6890835

SCHEMBL6890835

CCCCCCN1CCNC1=O

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.55
MEN1 O00255 3/20 0.55
FAAH O00519 3/20 0.51
NAAA Q02083 2/20 0.51
ALOX5 P09917 2/20 0.45
GBA1 P04062 1/20 0.42
PTGS1 P23219 3/20 0.41
PTGS2 P35354 3/20 0.41
MGLL Q99685 3/20 0.41
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
POLB P06746 2/20 0.40
ALDH1A1 P00352 1/20 0.40
PLA2G2A P14555 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9615745 1.00 KMT2A (0.55) KMT2AMEN1FAAHNAAAALOX5
SCHEMBL25752209 1.00 KMT2A (0.55) KMT2AMEN1FAAHNAAAALOX5
SCHEMBL17003978 1.00 KMT2A (0.55) KMT2AMEN1FAAHNAAAALOX5
SCHEMBL6269938 1.00 KMT2A (0.55) KMT2AMEN1FAAHNAAAALOX5
SCHEMBL10745323 1.00 KMT2A (0.55) KMT2AMEN1FAAHNAAAALOX5
SCHEMBL8671910 1.00 KMT2A (0.55) KMT2AMEN1FAAHNAAAALOX5
SCHEMBL8587006 1.00 KMT2A (0.55) KMT2AMEN1FAAHNAAAALOX5
SCHEMBL10868669 1.00 KMT2A (0.55) KMT2AMEN1FAAHNAAAALOX5
SCHEMBL6561471 1.00 KMT2A (0.55) KMT2AMEN1FAAHNAAAALOX5
SCHEMBL3420576 0.98 KMT2A (0.56) KMT2AMEN1FAAHNAAAALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0743956-A4 PRETARGETING METHODS AND COMPOUNDS NEORX CORP (US) 1999-03-24 EP claimed
EP-0743956-A1 PRETARGETING METHODS AND COMPOUNDS NeoRx (US) 1996-11-27 EP claimed
JP-10001426-A None JP disclosed
US-20230203087-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2023-06-29 US disclosed
US-20230203087-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2023-06-29 US disclosed
US-20230203484-A1 DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO WAVE LIFE SCIENCES LTD. (SG) 2023-06-29 US disclosed
US-20230203484-A1 DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO WAVE LIFE SCIENCES LTD. (SG) 2023-06-29 US disclosed
US-11236039-B2 Multi-step process for converting cyclic alkyleneureas into their corresponding alkyleneamines NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2022-02-01 US disclosed
EP-0906015-A4 LIVER RETENTION CLEARING AGENTS NEORX CORP (US) 2004-05-12 EP disclosed
EP-0914042-A4 CLUSTER CLEARING AGENTS NEORX CORP (US) 2000-10-25 EP disclosed
EP-0794788-A4 HEPATIC-DIRECTED COMPOUNDS AND REAGENTS FOR PREPARATION THEREOF NEORX CORP (US) 2000-05-24 EP disclosed
WO-1997046098-A9 CLUSTER CLEARING AGENTS 1998-08-06 WO disclosed
JP-H101426-A HAIR TREATMENT COMPOSITION KAO CORP 1998-01-06 JP disclosed
WO-1997046098-A1 CLUSTER CLEARING AGENTS NEORX CORPORATION (US) 1997-12-11 WO disclosed
WO-1997046099-A1 LIVER RETENTION CLEARING AGENTS NEORX CORPORATION (US) 1997-12-11 WO disclosed
EP-0794788-A1 HEPATIC-DIRECTED COMPOUNDS AND REAGENTS FOR PREPARATION THEREOF NEORX CORPORATION (US) 1997-09-17 EP disclosed
EP-0743956-A1 PRETARGETING METHODS AND COMPOUNDS NeoRx (US) 1996-11-27 EP disclosed
WO-1996017613-A1 HEPATIC-DIRECTED COMPOUNDS AND REAGENTS FOR PREPARATION THEREOF NEORX CORPORATION (US) 1996-06-13 WO disclosed
US-3932452-A 1-Arylmethyl-2-imidazolidinones MORTON-NORWICH PRODUCTS, INC. (US) 1976-01-13 US disclosed
US-3932452-A 1-Arylmethyl-2-imidazolidinones MORTON-NORWICH PRODUCTS, INC. (US) 1976-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11236039-B2 Multi-step process for converting cyclic alkyleneureas into their corresponding alkyleneamines ALKBH1, ALKBH3, ALKBH2 KMT2A 529/4885MEN1 1361/4885FAAH 1162/4885
US-20230203087-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF RNGTT, NSUN2, ALKBH1 KMT2A 742/4885MEN1 3176/4885FAAH 4105/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.