Acrylic Acid Methyl Ester

Acrylic Acid Methyl Ester

SCHEMBL1486038

C=C(CC=C(C)C(=O)O)C(=O)OCC.C=CC(=O)OC

nearest known ligand 0.39

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Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.39
CYP2C19 P33261 1/20 0.39
ALDH1A1 P00352 3/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
GLO1 Q04760 1/20 0.33
TSHR P16473 2/20 0.32
HPGD P15428 1/20 0.32
EGLN1 Q9GZT9 1/20 0.31
MAPT P10636 2/20 0.31
ALOX15 P16050 1/20 0.30
HSD17B10 Q99714 1/20 0.30
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid Ethyl Ester SCHEMBL1486045 0.92 NPSR1 (0.38) CYP2D6CYP2C19ALDH1A1SMN1; SMN2NPSR1
Acrylic Acid Ethyl Ester SCHEMBL1486048 0.89 TSHR (0.35) CYP2D6CYP2C19ALDH1A1NPSR1TSHR
Acrylic Acid Methyl Ester SCHEMBL1486047 0.88 ALDH1A1 (0.34) ALDH1A1ALOX15HSD17B10
SCHEMBL6386586 0.88 CYP2D6 (0.42) CYP2D6CYP2C19ALDH1A1SMN1; SMN2NPSR1
Acrylic Acid Methyl Ester SCHEMBL9150264 0.87 TSHR (0.48) ALDH1A1NPSR1TSHRHPGDMAPT
Acrylic Acid Ethyl Ester SCHEMBL6017688 0.86 ALOX15 (0.35) CYP2D6CYP2C19ALDH1A1NPSR1TSHR
Acrylic Acid Ethyl Ester SCHEMBL9698333 0.86 TSHR (0.33) CYP2D6CYP2C19ALDH1A1NPSR1TSHR
SCHEMBL6932684 0.86 ALDH1A1 (0.44) CYP2D6CYP2C19ALDH1A1SMN1; SMN2NPSR1
Methacrylic Acid SCHEMBL9472728 0.85 CYP2D6 (0.40) CYP2D6CYP2C19ALDH1A1SMN1; SMN2NPSR1
SCHEMBL8584132 0.83 ALDH1A1 (0.40) CYP2D6CYP2C19ALDH1A1SMN1; SMN2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1881780-B1 LONG WEARING GLOSSY COSMETIC COMPOSITION ELC MAN LLC (US) 2016-10-26 EP claimed
US-8932570-B2 Long-wearing glossy cosmetic composition ELC MANAGEMENT LLC (US) 2015-01-13 US claimed
US-20110073126-A1 Long-Wearing Glossy Cosmetic Composition ELC MANAGEMENT LLC 2011-03-31 US claimed
EP-1881780-A1 LONG WERAING GLOSSY COSMETIC COMPOSITION ELC Management LLC (US) 2008-01-30 EP claimed
WO-2006124706-A1 LONG WERAING GLOSSY COSMETIC COMPOSITION ELC MANAGEMENT LLC (US) 2006-11-23 WO claimed
US-20060257342-A1 Long-wearing glossy cosmetic composition ELC MANAGEMENT LLC 2006-11-16 US claimed
EP-1881780-B1 LONG WEARING GLOSSY COSMETIC COMPOSITION ELC MAN LLC (US) 2016-10-26 EP disclosed
US-8932570-B2 Long-wearing glossy cosmetic composition ELC MANAGEMENT LLC (US) 2015-01-13 US disclosed
US-20110073126-A1 Long-Wearing Glossy Cosmetic Composition ELC MANAGEMENT LLC 2011-03-31 US disclosed
EP-1881780-A1 LONG WERAING GLOSSY COSMETIC COMPOSITION ELC Management LLC (US) 2008-01-30 EP disclosed
WO-2006124706-A1 LONG WERAING GLOSSY COSMETIC COMPOSITION ELC MANAGEMENT LLC (US) 2006-11-23 WO disclosed
US-20060257342-A1 Long-wearing glossy cosmetic composition ELC MANAGEMENT LLC 2006-11-16 US disclosed